BACKGROUND Human chorionic gonadotropin (HCG), one of the initial embryonic signals, is probably a major regulator of the embryo-endometrial relationship. This study aims to assess the advantage of HCG supplementation during the secretory phase of hormonally prepared cycles for the transfer of cryopreserved-thawed embryos. MATERIALS AND METHODS This study was a randomized clinical trial. Infe...

Maternal heat stress in cattle may disrupt pregnancy by elevating uterine prostaglandin F(2 alpha) (PGF(2 alpha)) secretion. The objectives of this study were to determine the effects of elevated temperature (42 degrees C) in vitro upon 1) prostaglandin secretion by endometrial tissue; 2) the actions of extracellular regulators of uterine PGF [conceptus secretory proteins (bCSPs) and platelet-a...

We have determined uterine glycogen content, metabolizing enzyme expression and activity in the mink, a species that exhibits obligatory embryonic diapause, resulting in delayed implantation. Gross uterine glycogen concentrations were highest in estrus, decreased 50% by diapause and 90% in pregnancy (P ≤ 0.05). Endometrial glycogen deposits, which localized primarily to glandular and luminal ep...

introduction: to evaluate the efficacy and safety of carboplatin plus paclitaxel in patients with advanced locoregional recurrence and metastatic endometrial cancer. patient and method: 32 eligible patients (median age 62, range 41-72) with measurable endometrial cancer were treated with carboplatin (auc= 6) and paclitaxel (175 mg/m 3 ) every 4 weeks for 6 cycles, or, until disease progression ...

OBJECTIVE To investigate the reproductive outcome of artificial endometrial preparation with exogenous steroids for frozen-thawed embryo transfer with and without pre-treatment with depot gonadotropin releasing hormone agonist (GnRH-a) in women with regular menses. MATERIALS AND METHODS This is a prospective randomized clinical trial conducted in two ART centers on 176 women undergoing frozen...

OBJECTIVE To study whether an injury-induced inflammation might be the mechanism underlying the favorable effect of endometrial biopsy on the implantation rate in in vitro fertilization (IVF) patients. DESIGN Controlled clinical study. SETTING A medical center IVF unit and a research institute. PATIENT(S) Women undergoing IVF who had previous failed treatment cycles. INTERVENTION(S) End...

Preparation for embryo implantation requires extensive adaptation of the uterine microenvironment. This process consists of cell proliferation and cell differentiation resulting in the transformation of endometrial fibroblasts into a new type of cell called decidual cell. In the present study, we followed the space-time distribution of versican and hyaluronan (HA) in different tissues of the ut...

A cell line of human endometrial adenocarcinoma (HEC1), established by Kuramoto et al. in 1968, was studied. The presence of estradici receptors in these cells was documented. The receptors were found to reside mainly in the nucleus, even when cells were grown in estrogenfree medium. Isolated nuclei from HEC cells could be labeled during incubations with [3H]estradiol at 0-4°.The induction of ...

s of the 13th Red Lara Taller General, Buenos Aires, Argentina, 26-28 April 2017 P-02. Vaginismus in Assisted Reproductive Technologies Centers: an invisible population to be cared M.C.B. de Souza1, M.C.G. Gusmão1, R.A. Antunes1, M.M. de Souza1, A.L.S. Rito1, P. Lira1, A.C.A. Mancebo1, M.A. Tamm1, T.R. Panaino1, M.J. Bahia1 1Fertipraxis Reprodução Humana, Rio de Janeiro, Brazil. Objective: Geni...