Endothelial dysfunction is a pathological entity that multiply affects the health status. Erectile dysfunction is being recognized as a condition that is strongly interrelated with endothelial dysfunction, being a vascular event itself. Oral pharmacotherapy for erectile dysfunction has provided us with a new armamentarium on this condition. Phosphodiesterase 5 inhibitors have been investigated ...

normal 0 false false false en-us x-none fa background : circulating endothelial cells (cecs) and e-selectin are known as sensitive and specific markers of endothelial dysfunction. this study investigated whether cecs and e-selectin are surrogate biomarkers of preeclampsia and if measurement of cecs and e-selectin, early in the third trimester, could be a means of predicting preeclampsia. method...

Agrowing body of evidence suggests that endothelial dysfunction is associated with cardiovascular events. Endothelial dysfunction can be regarded as a syndrome that exhibits systemic manifestations associated with significant morbidity and mortality. The concept of endothelial dysfunction should be extended beyond the conduit vessels into the vascular wall and even to the bone marrow and the pr...

Endothelial dysfunction is a pathological entity that multiply affects the health status. Erectile dysfunction is being recognized as a condition that is strongly interrelated with endothelial dysfunction, being a vascular event itself. Oral pharmacotherapy for erectile dysfunction has provided us with a new armamentarium on this condition. Phosphodiesterase 5 inhibitors have been investigated ...

Endothelial dysfunction, one of many causes arterial changes in end-stage kidney disease (kidney failure), is a likely link between early vascular aging and the risk thrombosis or bleeding this condition. To evaluate this, we compared links stiffness endothelial/coagulation factors 55 patients receiving hemodialysis therapy 57 age-/sex-matched control individuals. Arterial was assessed from car...

Acute mental stress can impair arterial function (e.g., stiffness and endothelial function) transiently. Repeated exposures to stress-induced transient vascular dysfunction in daily life potentially leads persistent dysfunction, which increases the risk of cardiovascular disease. Therefore, it is important devise an effective strategy protect vasculatures from stress, exercise one possible solu...

BACKGROUND Chronic heart failure (CHF) induces endothelial dysfunction in part because of decreased nitric oxide (NO(·)) production, but the direct link between endothelial dysfunction and aggravation of CHF is not directly established. We previously reported that increased NO production via inhibition of protein tyrosine phosphatase 1B (PTP1B) is associated with reduced cardiac dysfunction in ...

Endothelial dysfunction is a predisposing factor for atherosclerosis and other cardiovascular diseases; and at the same time, endothelial dysfunction is associated to obesity. The prevalence of endothelial dysfunction, atherosclerosis and obesity is quite high among Mexican children; on the other hand, gut microbiota has been associated to obesity in the same population. Atherosclerosis is asso...

The endothelium is a complex organ with a multitude of properties essential for control of vascular functions. Dysfunction of the vascular endothelium is regarded as an important factor in the pathogenesis of diabetic micro- and macro-angiopathy. Endothelial dysfunction in Type I and II diabetes complicated by micro- or macro-albuminuria is generalized in that it affects many aspects of endothe...

Since its initial description by our laboratory, now 27 years ago, much has been learned about the causes and consequences of human endothelial dysfunction. Impairment of endothelial function assessed by nitric oxide bioavailability (referred to as endothelial dysfunction) has been observed in atherosclerosis, is associated with traditional risk factors, and has been described in the setting of...