MicroRNAs (miRNAs) are a type of noncoding RNA participating in the post-transcriptional regulation gene expression that regulates plant responses to salt stress. Small sequencing was performed this study discover miRNAs responding stress Taxodium hybrid ‘Zhongshanshan 405’, which is tolerant salinity A total 52 were found be differentially expressed. The target genes enriched with ontology (GO...

In mammals, DNA methylation is associated with aging. However, age-related changes during phase transitions largely remain unstudied in plants. Moso bamboo (Phyllostachys edulis) requires a very long time to transition from the vegetative floral phase. To comprehensively investigate association of aging, we present here single-base-resolution profiles using both high-throughput bisulfite sequen...

Abstract Background : Cervical cancer is the fourth commonly occurred in women around world. However, it still lacks effective approaches to improve current prognosis of cervical and prevent metastasis. Objective We aim discover a promising biomarker for by utilizing bioinformatics analysis. Methods Gene expression was analyzed datasets from The Cancer Genome Atlas Program-Cervical squamous cel...

An investigation of the effects two important post-transcriptional regulatory mechanisms, gene transcription and alternative splicing (AS), on wood formation Eucalyptusurophylla × tereticornis, an economic tree species widely planted in southern China, was carried out. We performed RNA-seq E. urophylla tereticornis hybrids with highly contrasting basic density (BD), cellulose content (CC), hemi...

Glioma is the most common malignant tumor in the central nervous system. This study aims to explore the potential mechanism and identify gene signatures of glioma. The glioma gene expression profile GSE4290 was analyzed for differentially expressed genes (DEGs). Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were applied for the enriched pathways. A protein-prote...

A system for the automatic creation of Pictorially Enriched Ontologies is presented, that is ontologies for context-based video digital libraries, enriched by pictorial concepts for video annotation, summarization and similarity-based retrieval. Extraction of pictorial concepts with video clips clustering, ontology storing with MPEG-7, and the use of the ontology for stored video annotation are...

To investigate the regulation of endothelial cell (EC) microRNAs (miRNAs) altered by heat stress, miRNA microarrays and bioinformatics methods were used to determine changes in miRNA profiles and the pathophysiological characteristics of differentially expressed miRNAs. A total of 31 differentially expressed miRNAs were identified, including 20 downregulated and 11 upregulated miRNAs. Gene Onto...

The present study aimed to examine the changes in DNA methylation of gene promoters associated with type 2 diabetes (T2D). The DNA methylation profile dataset GSE38291 was downloaded from the Gene Expression Omnibus database. A paired t-test was used to analyze differences in the DNA methylation of gene promoters between T2D and normal muscle samples. Gene Ontology (GO) enrichment analysis was ...

gene identification represents the first step to a better understanding of the physiological role of the underlying protein and disease pathways, which in turn serves as a starting point for developing therapeutic interventions. familial hypercholesterolemia is a hereditary metabolic disorder characterized by high low-density lipoprotein cholesterol levels. hypercholesterolemia is a quantitativ...