Molecular oxygen (O2) is the premier biological electron acceptor that serves vital roles in fundamental cellular functions. However, with the beneficial properties of O2 comes the inadvertent formation of reactive oxygen species (ROS) such as superoxide (O2*-), hydrogen peroxide, and hydroxyl radical (OH*). If unabated, ROS pose a serious threat to or cause the death of aerobic cells. To minim...

It is well known that oxidative stress (OS), defined as an imbalance between radicals and antioxidant defense, is implicated as a pathophysiological mechanism of different diseases and is a topic of growing interest. Cell injury is a consequence of OS; recognized targets are DNA, lipids and proteins, which react with hydroxyl radicals to form specific products1. Especially in the field of cardi...

BACKGROUND The association between hypertension and diabetes has been linked to increased oxidative stress with age. This study was to examine the level of age-dependent alterations in antioxidant defense system between patients having hypertension and/or type-2 diabetes. METHODS The study was conducted at the Ahmadu Bello University Teaching Hospital, Zaria-Nigeria, using 200 Subjects recrui...

Reactive oxygen species can be produced in leaf cells during normal aerobic metabolism or in a variety of exogenous factors, which may cause oxidative damage to plants, unless they have an efficient antioxidant defense system, consisting of enzymatic and non-enzymatic substances. This work raised the hypothesis that plants of Ipomoea nil cv. Scarlet O'Hara, a native species and ornamental vine ...

background: diazinon (dzn) is one of the most organophosphates (ops) insecticides that widely used in agriculture and industry. some ops are capable to produce free radicals and induce malfunction in body antioxidant systems. enzymatic and nonenzymatic antioxidants such as superoxide dismutase (sod), catalase (cat) and glutathione s-transferase (gst) and glutathione (gsh) normally counteract da...

Introduction: Huntington's disease is a neurodegenerative disorder in which an increase in the global oxidative stress and a decrease in the antioxidant defense system are observed. Olea europaea's main phenolic components include oleuropein, dimethyl oleuropein, ligstroside and phenolic oleosides, which can be more than 140 mg per gram of fresh olives and 60-90 mg per gram of dried olive le...

BACKGROUND Pterygium is a disorder of the ocular surface induced by chronic exposure to UV-light. Abundant data is available from patients with primary pterygium, but scarce from those with recurrent pterygium. The present study aimed to explore the oxidant/antioxidant status in tissue of primary and recurrent pterigium in men and women. METHODS Pathological tissue samples were taken during s...

Sapodilla is one of the important fruit crops in tropical area which has problem with seed germination. So Manilkara hexandra (kherol) is generally used as a rootstock for sapodilla. This experiment was performed to assess the morphological changes and antioxidant enzymatic activity of Manilkara hexandra seedling under salinity condition. A pot experiment was carried out in a greenhouse using d...

Now-a-days, there is an increased occurrence of various diseases like cardiovascular disease, neurological disorders, cancer, diabetes and autoimmune disease due to the presence of free radicals. Bandyopadhyay et al. [1]. Antioxidant is defined as the agent that neutralizes the effect produced by free radical Fang Y et al. [2]. The antioxidant can be classified into two categories, namely enzym...

cardiovascular diseases with an incidence of approximately 50% are the main causes of death in most advanced countries and an increasing trend in the developing world as well. the world health organization estimates that 12 million people per year worldwide die from cardiovascular diseases. cardiovascular diseases are becoming an increasing problem worldwide and hypercholesterolemia has been co...