We evaluated the incidence of eosinophilia (≥ 400 ~sl) in a stable chronic hemodialysis (CHD) group of 240 patients treated at a singular unit, and compared it with an age and sex mached control group of 189 non-renal outpatients. The incidence in the CHD patients was 13.75 Wa, compared to 2.11 Wa in the con trols (p <0.0002). Parasitic bowel disease was not present in the 35 eosinophilic patie...

A 7 year-old male presented with recurrent fever, cough and respiratory distress for over last 2 years. Based on extremely high eosinophil count, high Immunoglobulin E, increase in eosinophilic precursors in bone marrow, and positive antigen test for Wuchereria bancrofti, a diagnosis of Tropical Pulmonary Eosinophilia with Eosinophilic Leukemoid Reaction was made. Complete recovery was achieved...

RATIONALE Airway eosinophilia is typical of asthma, and many controller treatments target eosinophilic disease. Asthma is clinically heterogeneous, however, and a subgroup of people with asthma do not have airway eosinophilia. The size of this subgroup is uncertain because prior studies have not examined repeated measures of sputum cytology to determine when people with asthma have intermittent...

Idiopathic hypereosinophilic syndrome (IHES) is characterized by the triad of peripheral blood eosinophilia (> 1500 cells/μl) for more than 6 months, without any other discernible cause in association with signs and symptoms organ infiltration related to eosinophilia. IHES usually seen middle age group 20–50 years uncommon pediatric population. Herein, we report a case 12-year-old male child wh...

A 72 year old man developed acute organic brain syndrome associated with marked eosinophilia following self medication with a variety of drugs. Investigations revealed no other known causes of eosinophilia. Withdrawal of drugs resulted in dramatic drop in eosinophil count paralleled by clinical resolution of neurological problems. To our knowledge drug-induced eosinophilia has not previously be...

The diagnosis of eosinophilic pneumonia (EP) is rare and challenging. This condition is frequently misdiagnosed as pulmonary tuberculosis, lymphoma, schistosomiasis, Wegener's granuloma, severe acute respiratory syndrome, or severe community-acquired pneumonia. Herein, we report a case in which computed tomography (CT)-guided percutaneous lung biopsy was used to diagnose EP without alveolar eos...

PURPOSE Eosinophils function as an effector cell in the development of asthma and allergic disease. Eotaxins are cytokines that promote pulmonary eosinophilia via the receptor CCR3. Single-nucleotide polymorphisms (SNPs) in CCR3 and eotaxin genes are associated with asthma. In this study, genetic interactions among SNPs of several eotaxin genes and CCR3 were assessed and their relationship with...

Blood eosinophilia is diagnosed by an absolute eosinophil count that exceeds 0.5 × 109/L.1 Hypereosinophilia is classified as either primary, due to clonal expansion of eosinophils through acquisition of a somatic mutation (eg, FIP1L1-PDGFRA),1 or secondary, as seen in response to exogenous type 2 cytokines (eg, IL-3, IL-5, and GMCSF) secreted by various cells (eg, T-lymphocytes).2-4 Secondary ...

BACKGROUND Eosinophilia occurs in a wide variety of situations such as parasitic infections, allergic disorders, and malignancies. Most cases of eosinophilia of parasitic origin, especially those with a tissue migration life cycles consists of human infections by helminth parasites. The aim of present study was to determine the parasitic causes of eosinophilia in patients in a major endemic are...

BACKGROUND Among immigrants of sub-Saharan origin, parasitic infection is the leading cause of eosinophilia, which is generally interpreted as a defense mechanism. A side effect of the inflammatory mediators released by eosinophils is damage to host organs, especially the heart. The main objectives of this study were to i) assess cardiac involvement in asymptomatic sub-Saharan immigrants with e...