background and objectives: dermatophytes possess a wide array of virulence factors and various antifungal susceptibility patterns which influence their pathogenesis in humans and animals. the aim of this study was to evaluate antifungal suscep- tibility and keratinase and proteinase activity of 49 dermatophyte strains from the genera microsporum , trichophyton and epidermophyton which were isol...

BACKGROUND Surveillance of dermatophytosis is essential to determine the likely changes in etiological trends and distribution profile of this infection. In this study beta tubulin gene (BT2), was used as the first time in a PCR-RFLP format to clarify the distribution of dermatophytosis agents in some parts of Iran. METHODS A total of 603 clinical isolates was obtained from 500 patients in Te...

Contact-sensing or thigmotropism is the directional growth response of cells in relation to topographical guidance cues. Thigmotropism is thought to play a major role in the location of infectable sites on plants by phytopathogenic fungi and has recently been shown to be a property of hyphae in the human pathogenic fungus Candida albicans. Here we show that hyphae of the dermatophytes Epidermop...

The aim of the present study was to investigate anti fungal activities of the fresh extract of Allium ascalonicum Linn. (Liliaceae) against clinically important yeast, dermatophytes and some saprophytic fungi in vitro. The anti fungal effects of fresh crude juice of shallot were determined against 11 isolates of Candida albicans, three species of dermatophytes (Microsporum gypseum, Trichophyton...

Multi-target strategies are directed toward targets that are unrelated (or distantly related) and can create opportunities to address different pathologies. The antidermatophytic activities of nine natural skin lighteners: α-bisabolol, kojic acid, β-arbutin, azelaic acid, hydroquinone, nicotinamide, glycine, glutathione and ascorbyl tetraisopalmitate, were evaluated, in comparison with the know...

Random samples of the weekly entry of bathers to a swimming pool were examined for tinea pedis and verruca before and at intervals after the supply of individual sachets of foot powder to all bathers.Over three and a half years the overall incidence of tinea pedis decreased from 8.5% to 2.1%, and in adult males it decreased from 21.5% to 6.9%. The incidence of infection with Trichophyton mentag...

Evaluating the in vitro antifungal activity of Phlomis lanceolata, Rhynchocorys elephas, Otostegia persica and Eremurus persicus, four species used in Iranian Traditional Medicine, has been performed on the clinical isolates of the pathogenic fungi Aspergillus fumigatus, A. flavus, Trichophyton mentagrophytes, T. rubrum, T. verrucosum, Microsporum canis, M. gypseum and Epidermophyton floccosum ...

By condensing ethylene-1,2-diamine with different aldehydes such as benzaldehyde, 4-chloroacetophenone and 2-chlorobenzaldeyhde within 1:2 molar ratio, resulted new series of Schiff base ligands (L1)-(L3) containing bidentate nitrogen atom. Their metal complexes were synthesized by coordinating the transition metals Co(II), Cu(II), Ni(II) Zn(II) exhibited octahedral geometry. characterization w...

In order to provide an effective alternative for efficient management of dermatophytosis, we evaluate in vitro the antioxidant and antiradical potentials essential oil dry flower buds Syzygium aromaticum its antidermatophytic activity against Epidermophyton floccosum Trichophyton soudanense, For this purpose, was obtained by hydrodistillation through a Clevenger apparatus were evaluated ferric ...