21 A Matlab -based software package, EPILAB, was developed for supporting researchers 22 in performing studies on the prediction of epileptic seizures. It provides an intuitive and 23 convenient graphical user interface. Fundamental concepts that are crucial for epileptic 24 seizure prediction studies were implemented. This includes, for example, the development 25 and statistical validation of...

A new approach to recognize and predict succedent epileptic seizure by using single channel electroencephalogram (EEG) analysis is proposed. Spectral analysis of a brain time series of the left frontal FP1-F7 (LF) scalp location signal is devoted for seizure prediction and analysis. Important findings showing the presence of preictal spectral changes in studied brain signal are described. Spect...

PURPOSE To investigate the association between genotype (methyl-CpG-binding protein 2 (MECP2 gene mutation)) and epileptic seizure phenotype in Rett syndrome. METHODS We used the British Isles Rett syndrome survey to identify 137 subjects with one of the nine most frequent MECP2 gene mutations and invited their parents or carers to participate in a postal questionnaire and telephone interview...

This book is an ideal way for clinicians and researchers in epileptology to update themselves about current concepts and knowledge of pathophysiological seizure generation mechanisms and ongoing developments in seizure prediction strategies. The book especially highlights the importance of multidisciplinary teamwork involving experts in the neurosciences, mathematics, physics, and engineering (...

Psychogenic non-epileptic seizure (PNES), also known as pseudoseizure, pseudo-epileptic seizure and psychogenic seizure, is a psychologically based disorder accompanied with abnormal movements, sensations, emotions and/or behaviors that mimic epileptic seizures, but does not originate from a neurological disturbance (1-3). Psychogenic seizure, historically known as hysterical seizure (3, 4), is...

This paper presents a patient-specific epileptic seizure predication method relying on the common spatial pattern- (CSP-) based feature extraction of scalp electroencephalogram (sEEG) signals. Multichannel EEG signals are traced and segmented into overlapping segments for both preictal and interictal intervals. The features extracted using CSP are used for training a linear discriminant analysi...

Epileptic seizures can be evoked in chicks homozygous for the epileptic seizure gene (epi, epi) by elevating their body temperature using microwave diathermy. These seizures precede and differ in motor seizure pattern from a second clonic-tonic seizure produced by hyperthermia in both epileptic and carrier (heterozygote, Epi, epi) chicks. Hyperthermia did not evoke seizures in adult epileptic c...