purpose: to evaluate histopathological changes induced by 0.02% mitomycin-c (mmc) in rabbits corneas. methods: this study was performed on 48 corneas of 24 rabbits (dutch type, albino). under general anesthesia, lamellar keratectomy was performed and either mmc 0.02 % (mmc group) or balanced salt solution (control group) was applied to the stromal bed for one minute. sixty days later, light mic...

With the aid of the electron microscope, the ultrastructural changes associated with bullous keratopathy were studied in corneal specimens from a patient with congenital hereditary corneal dystrophy and from one with congenital glaucoma. Within the subepithelial bullae of both specimens, infoldings of the basal plasma membrane of the basal epithelial cells could be observed to contain basement-...

PURPOSE To describe a case of severe corneal granular dystrophy with clinicopathologic and molecular genetic findings. METHODS The DNAs of a 53-year-old male patient suffering from corneal granular dystrophy and nonaffected family members were analyzed by molecular genetic methods. Clinical features, and histopathologic and immunohistochemical findings from the penetrating keratoplasty specim...

A 29-year-old male was referred following a flap loss after the creation of a thin, irregular flap with a visual acuity of logMAR 0.1 with -2.0 DS-2.75 DC × 175°. Corneal topography and anterior segment optical coherence tomography revealed an irregular corneal curvature and epithelial profile. Phototherapeutic keratectomy (PTK) followed by Topography - Guided Custom Ablation Treatment (TCAT), ...

PURPOSE To report a patient with severe post-laser in situ keratomileusis (LASIK) epithelial ingrowth and keratolysis treated with flap amputation and phototherapeutic keratectomy (PTK) with adjuvant intraoperative mitomycin C (MMC). METHODS Case report. RESULTS A 55-year-old woman was referred to our department due to severe post-LASIK epithelial ingrowth with corneal melting 2 years after...

PURPOSE To evaluate epithelial healing, postoperative pain, and visual and refractive outcomes after photorefractive keratectomy (PRK) using three epithelial removal techniques. DESIGN Prospective, nonrandomized, comparative trial. METHODS SETTING Department of Ophthalmology, Yonsei University College of Medicine and Balgensesang Ophthalmology Clinic, Seoul, Korea. INTERVENTIONS For th...

PURPOSE To describe a topographically guided photorefractive keratectomy technique for the management of secondary hyperopia following radial keratectomy. METHODS A retrospective study was carried out in patients where a topographically guided photorefractive keratectomy technique was performed for the management of secondary hyperopia following radial keratectomy. The patients had preoperati...