recalcitrant gingival erythematous lichen planus lesions comprise a considerable therapeutic problem. this case of chronic desquamative gingivitis in a 25-year-old woman with erosive oral lichen planus was treated with topical and systemic corticosteroid administration, followed by placement of a free gingival graft on right upper quadrant. although recurrence of the lesions was observed follow...

BACKGROUND Oxidative stress is involved in oral lichen planus (OLP) pathogenesis; meanwhile anthocyanins are natural antioxidants present in grapes skin. OBJECTIVES The aim of this research was to verify the utility of anthocyanins, extracted from grapes skin, for the local treatment of oral lichen planus and to compare it with clobetasol propionate- neomycin -nystatin cream (CP-NN). STUDY ...

conclusions since ki-67 is extensively accepted as an important biomarker in diagnosis, prognosis and treatment of cancerous and precancerous lesions, a high degree of presence of this biomarker in chronic precancerous lesions, such as erosive olp, can be of great use in prognosis and suggested treatments. objectives this study aimed to evaluate ki-67 expression in erosive and non-erosive oral ...

A case of recurrent progressively severe ulceration secondary to erosive lichen planus is reported. The patient developed marked malnutrition as a result of extensive involvement of the oral cavity. In addition to the oral ulcerations, she also had violaceous spots present over her forearm. Treatment administered in view of histopathological report and clinical presentation, resulted in marked ...

Study objectives: Oral lichen planus (OLP) is a well recognized chronic mucocutaneous disorder which can manifest in the oral mucosa, whose exact pathogenic mechanisms have not been understood. Estimation of serum cortisol in patients with OLP may be helpful in understanding the pathogenesis. Therefore a study was undertaken to analyze the serum cortisol levels in OLP patients. An attempt was a...

I n May 2007, a 62-year-old man presented with a 6-cm fungating mass on the dorsum of the tongue (Figure 1), which had lasted for an unknown period of time. The lesion had a roughened and irregular surface, with areas of white keratosis admixed with areas of necrosis. It felt indurated on palpation. Two additional smaller exophytic lesions were observed on the dorsum of the tongue: one adjacent...

BACKGROUND Mucous membrane pemphigoid is a rare autoimmune blistering disease primarily affecting mucosal surfaces. Blistering and scarring may occur in the eyes, mouth, esophagus, larynx, and on the vulva. Scarring can result in severe structural changes to the vulva that may mimic the findings of other inflammatory dermatologic disorders of the vulva, including lichen sclerosus and lichen pla...

BACKGROUND The aim of this study was to evaluate the efficacy of a topical hyaluronic acid (HA) gel preparation (0.2%) in the management of oral lichen planus (OLP). METHODS A total of 124 patients with erosive OLP participated in a randomized, placebo-controlled, double-blind trial to evaluate the efficacy of a topical HA preparation. Outcome measures included soreness relief following immed...

OBJECTIVES To report on the prevalence of oral lichen planus among a sample of the Egyptian population. STUDY DESIGN 4470 Egyptian patients, aged 15-75 years, were seen at the outpatient clinic at the Faculty of Oral and Dental Medicine, Cairo University, Egypt. 31.25 % of these patients were males and 68.75% were females. Oral mucosal lesions consistent with oral lichen planus (OLP) were ide...

OBJECTIVES To evaluate the efficacy of 1% pimecrolimus cream in treating oral erosive lichen planus and to assess its tolerance. DESIGN Double-blind randomized trial with placebo control. SETTING Outpatients of the Department of Dermatology, University Hospital of Nice, from December 21, 2004, to April 19, 2005. PATIENTS Fourteen consecutive patients with oral erosive lichen planus confir...