A 70-year-old man was admitted to the Emergency Department (ED) for marked asthenia and severe anemia. In addition, a high level of lipase found. During hospitalization, locally advanced gastric cancer diagnosed, with endoscopic evidence large polyploid formation originating under cardias that occupied most lumen. total body CT scan performed before surgery; tumor affected posterior wall, tenac...

Purpose. Neuroendocrine neoplasms (NENs) of the esophagus are very uncommon with only a few studies published worldwide. Studies on clinical profile, management, and outcomes are very uncommon. Methods. We report the largest single institution retrospective review of 43 patients of pure esophageal NENs out of our registry of gastrointestinal neuroendocrine tumors treated between 2005 and 2014. ...

BACKGROUND: Most prevalent esophageal neoplasm is squamous cell carcinoma and adenocarcinoma. Other tumors are uncommon and poorly studied. Primary neuroendocrine esophageal neoplasm is a rare carcinoma and most of its therapy management is based on lung neuroendocrine studies. Neuroendocrine tumors can be clustered in the following subtypes: high grade (small cell carcinoma or large cell carc...

BACKGROUND Free jejunal transfer has become the standard technique for reconstruction of the pharynx and hypopharynx, especially with proximal neoplastic lesions, whereas gastric tube interposition is the technique of choice for reconstruction of the hypopharynx and cervical esophagus when resection extends below the thoracic inlet. HYPOTHESIS Surgical ablation is a viable option for advanced...

Recently, researchers have been increasingly focusing on microRNAs (miRNAs) with accumulating evidence indicating that miRNAs serve as a vital role in various biological processes and dysfunctions of miRNAs are closely related with human complex diseases. Predicting potential associations between miRNAs and diseases is attached considerable significance in the domains of biology, medicine, and ...

Esophageal cancer is one of the most lethal of all neoplasms. During the last two decades, there have been significant changes in the epidemiology and treatment of esophageal cancer. The incidence of adenocarcinoma is increasing whereas that of squamous cancer is decreasing. Surgery, the mainstay of treatment of esophageal cancer, has been used with neoadjuvant chemoradiotherapy to improve prog...

Background & Aims Esophageal endoscopic submucosal dissection (ESD) can be challenging, and technique innovation is needed to make it easier perform, especially in the West, where experience procedure volumes are less. The loose esophageal submucosa allows easy entry of entire ceramic tip an insulated-tip (IT) knife, allowing electrocautery blade dissect submucosa, while protects muscle layer. ...

Abstract Background Leiomyomas are the most common benign esophageal tumors originating from muscular layer. They rare lesions that constitute less than 1% of neoplasms. In one-third patients leiomyomas occur at level gastroesophageal junction. Minimally invasive surgery is considered today treatment choice with laparoscopic approach used for distal tumors. Methods We present case a 79-year-old...