Gastroesophageal reflux refers to the passage of gastric contents including food, acid, and digestive enzymes up into the esophagus. Reflux is most commonly recognized in infants when it is associated with regurgitation, known as "spitting up," and it is usually a self-limited, benign process that has little or no effect on normal weight gain or development. Adults and adolescents may also have...

Gastroesophageal reflux disease (GERD) is one of the most common reasons for referral to a physician. reflux-associated extraesophageal symptoms occur in every third patient with GERD. Diagnostic difficulties and prescription effective treatment rapid resolve GERD are still important issues when managing these patients. This paper summarizes data on prevalence pattern symptoms, as well efficacy...

Introduction. The pathogenesis of GERD is strongly related with mixed acid and bile reflux. Benign and malignant esophageal and gastric lesions have been associated with synergetic activity between those parameters. Bile reflux causes reactive gastropathy evaluated with Bile Reflux Index (BRI). The aim was to investigate if the sequence: bile reflux-intestinal metaplasia-GERD-esophagitis, is as...

BACKGROUND AND AIM Patients with gastroesophageal reflux disease (GERD) usually suffer from acid reflux and duodenogastroesophageal reflux (DGER) simultaneously. The question of whether DGER has an important effect on the development of GERD remains controversial. The aim of the present study was to investigate the role of DGER in the pathogenesis of GERD and its value for the diagnosis of none...

The relationship between Helicobacter pylori (Hp) gastritis and gastroesophageal reflux disease (GERD) remains controversial. The aim was to investigate the association between Hp infection and gastroesophageal reflux (GER) and the impact of Hp eradication on esophageal acid exposure and motility in adolescents and young adults with Hp gastritis and GERD. Sixty-four patients with symptoms sugge...

A 6-year-old boy presented with nocturnal cough of 8 months duration. Upper gastrointestinal endoscopy (UGIE) showed an esophagogastric polyp and esophagitis. The 24 hours ambulatory pH recording revealed moderate gastro esophageal reflux (GER) and esophageal manometry demonstrated hypotensive lower esophageal sphincter (LES). A diagnosis of gastroesophagel reflux disease (GERD) with hypotensiv...

Transient lower esophageal sphincter (LES) relaxation (TLESR) is defined as LES relaxation without a swallow. TLESRs are observed in both of the normal individuals and the patients with gastroesophageal reflux disorder (GERD). However, TLESR is widely considered as the major mechanism of the GERD. The new equipments such as high resolution manometry and impedance pH study is helped to understan...

introduction: gastro-esophageal reflux (ger) is common among children of different ages and treatment is necessary since it could turn in to gastroesophageal reflux disease (gerd) and cause complications. in patients that do not respond to medical treatment and patients that have complications such as repeated apnea, pneumonia, stricture caused by esophagitis and failure to thrive, surgical tre...

The surgical indications for the treatment of gastroesophageal reflux disease (GERD) in patients with esophageal motility disorders have been debated. We report a case of antireflux surgery performed in a patient with absent esophageal motility as categorized by the Chicago classification (2011). A 54-year-old man underwent laparoscopic Toupet fundoplication due to apparent GERD and desire to d...

c 2017 The Korean Society of Neurogastroenterology and Motility J Neurogastroenterol Motil, Vol. 23 No. 4 October, 2017 www.jnmjournal.org Stress exacerbates heartburn symptoms in gastroesophageal reflux disease (GERD) patients and also affects visceral sensitivity. The mechanism of visceral hypersensitivity in functional gastrointestinal disorders and functional heartburn remains unclear. Howe...