The National Bioethics Advisory Commission has proposed that regulatory oversight for research with human subjects be extended beyond the protection of individual research participants to include the protection of social groups. To accomplish this, the commission recommends that investigators and ethics review boards a) work directly with community representatives to develop study methods that ...

advancements in different field of medicine have given rise to complex ethical dilemmas in clinical practice. the more the clinicians are sensitized to ethical problems and familiar with ethical decision-making, the more they can value professionalism in their practice. the current paper is designed to emphasize physicians to think ethically in the field of internal medicine and endocrinology. ...

An ethical issue is an identifiable situation and also an opportunity which requires an individual or organization to choose from the actions that must be evaluated as right or wrong, ethical or unethical, etc. Product– related ethical issues arise when marketers fail to disclose the risks associated with a product. In pricing, common ethical issues are price fixing or failure to disclose the f...

The Good Clinical Practices (GCP) codes of the WHO and the International Conference of Harmonization set international standards for clinical research. But critics argue that they were written without consideration for the challenges faced in low and middle income countries (LMICs). Based on our field experience in LMICs, we developed a non-exhaustive set of recommendations for the improvement ...

Eight research protocols which had previously been approved by Ethical Research Committees (ERCs) were reviewed in simulated review committees set up during a symposium on medical ethics. Only three protocols were considered to provide fully adequate information to allow ethical review and only one protocol was thought to provide sufficient guarantees on the ethical issues raised by the propose...

The present commentary is based on the following considerations: 1) for the purposes of authorisation, a distinction is drawn between "research" and "intervention". The procedures for authorising the former are more complex, the relevant controls are stricter and approval has to be granted by a Research Ethics Committee (REC); 2) although the debate is still open, it is barely credible to claim...

This report provides practical guidance on refinement of the use of food and fluid control as motivational tools for macaques used in behavioural neuroscience research. The guidance is based on consideration of the scientific literature and, where data are lacking, expert opinion and professional experience, including that of the members of a Working Group convened by the United Kingdom Nationa...

background: dealing with ethical considerations is a major component of health technology assessment (hta) definitions. objectives: present study aimed to explore and describe the manner of ethical analyses in hta reports and the effects it had on hta-related decision making around the world.   methods: by considering the contextual milieu of reports and searching for ethical themes and subject...

The demand and growth for published research in the field of multiple sclerosis (MS) has increased exponentially over the last few years. The primary aim of the Multiple Sclerosis Journal (MSJ) has always been to reflect the excellent work of the ever-expanding and diverse clinical and research field of MS, and this role will now be shared by MSJ’s companion journal MSJ Experimental, Translatio...