BACKGROUND A patient presented with severe acidosis and a point-of-care lactate measurement of 42 mmol/L. Mesenteric ischemia was suspected, with a potential need for laparotomy; however, plasma lactate measurements were below 4 mmol/L. Ethylene glycol ingestion was subsequently diagnosed. We therefore wished to determine why discrepancies in lactate measurements occur and whether this "lactate...

The liquefaction of crop residues in the presence of ethylene glycol, ethylene carbonate, or polyethylene glycol using sulfuric acid as a catalyst was studied. For all experiments, the liquefaction was conducted at 160°C and atmospheric pressure. The mass ratio of feedstock to liquefaction solvents used in all the experiments was 30:100. The results show that the acid catalyzed liquefaction pro...

Considerable interest has recently been evoked in the study of proteins in nonaqueous solvents, very largely as a result of the observations of Rees and Singer (1) and Yang and Doty (2) that the internal configuration of protein molecules could be radically altered in nonaqueous media, as reflected by changes in sedimentation constants, viscosity increments, and optical rotatory dispersion. Of ...

Intercellular communication most likely plays a significant coordinating role in morphogenesis. Blockage of a specific type of intercellular communication, that mediated by gap junctions, has been proposed as a mechanism of action of some teratogens. Several glycol ethers have recently been shown to be teratogenic in laboratory animals. Because these compounds are negative in genotoxic assays, ...

Semen was diluted 1:9 with egg yolk-citrate medium containing 0.31--3.1 M (final concentration) formamide, butyramide, acetamide, propionamide, dimethylformamide, lactamide, malomide, ethylene glycol, trimethylene glycol, dimethylsulphoxide (DMSO) or glycerol. After 30 min incubation at 20 degrees C, sperm motility was superior in hypertonic solutions of acetamide, lactamide, dimethylsulphoxid...

Background: The management of methanol and ethylene glycol poisoning includes inhibition of alcohol dehydrogenase by IV ethanol therapy or fomepizole. There is a lack of contemporary information on IV administration of ethanol in this setting. Objective: To evaluate the effectiveness of IV ethanol therapy in combination with hemodialysis for the treatment of methanol and ethylene glycol poisoni...

Ethylene glycol poisoning is a rare yet potentially fatal illness seen most commonly in association with ingestion by alcoholics or in suicide attempts. It is characterized by an elevated anion gap metabolic acidosis, osmolal gap, calcium oxalate crystals in the urine, and a well-defined clinical picture. Prompt treatment is crucial because effective intervention can prevent the neurologic, car...