Abstract Background Pediatric expiratory central airway collapse poses diagnostic challenge due to non-specific clinical presentation with further investigations needed for definite diagnosis. The purpose of this cross-sectional study was determine the accuracy 320-row multidetector free-breathing cine CT in diagnosis pediatric utilizing its advantageous wide z -axis coverage. End-inspiratory a...

   Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    The purpose of this study was to determine the extent of change...

A randomized, double-blind, crossover trial was designed to compare the acute effects of Combivent and salbutamol on spirometric parameters in patients with moderate to severe asthma. Nineteen patients with a mean baseline forced expiratory volume in 1 sec. (FEV]) less than 65% predicted, were randomized on two separate days to receive two puffs of salbutamol (200 µg) or two puffs of Combiv...

PURPOSE OF REVIEW To compare the positive end-expiratory pressure selection aiming either to oxygenation or to the full lung opening. RECENT FINDINGS Increasing positive end-expiratory pressure in patients with severe hypoxemia is associated with better outcome if the oxygenation response is greater and positive end-expiratory pressure tests may be performed in a few minutes. The oxygenation ...

In normal humans during quiet breathing, expiration is mostly driven by elastic recoil of the lungs. Expiration becomes active when ventilation must be increased to meet augmented metabolic demands, or in response to expiratory loading, be it experimental or disease-related. The response to expiratory loading is considered to be mediated by both reflex and cortical mechanisms, but the latter ph...

The effects of pulse lung inflation (LI) on expiratory muscle activity and phase duration (Te) were determined in anesthetized, spontaneously breathing dogs (n = 20). A volume syringe was used to inflate the lungs at various times during the expiratory phase. The magnitude of lung volume was assessed by the corresponding change in airway pressure (Paw; range 2-20 cmH(2)O). Electromyographic (EM...

Introduction: Renal failure affects the mechanical and the ventilatory function of the lungs. A few studies have evaluated the ventilatory and pulmonary function in dialysis patients. The present study aimed to compare Pulmonary Function Test (PFT) results in patients undergoing Hemodialysis (HD) and Peritoneal Dialysis (PD). Materials and Methods: We conducted a cross-sectional study on 50  pa...

Introduction: Forced expiratory value in one score  (FEV1)/ Forced vital capacity (FVC) was used in classical literature for primary classifications of pulmonary disorders. American Thoracic Society/ European Respiratory Society guidelines recommended using FEV1/VC instead of FEV1/FVC.The aim of study was determination of the extent of superiority of FEV1/VC over the FEV1/FVC. Materials and Met...