the aim of this study is to assess cost-effectiveness of infliximab, compared with conventional treatments in patients with moderate to severe ulcerative colitis (uc) in iran. we developed an analytical decision model with a 5-year-time horizon to follow up 1000 hypothetical patients, in order to estimate treatment costs and outcomes. hypothetical patients, were individuals with moderate to sev...

OBJECTIVE To estimate the cost-effectiveness of extended adjuvant letrozole in postmenopausal women with early breast cancer and estrogen or progesterone receptor-positive tumors who had completed 5 years of adjuvant tamoxifen. STUDY DESIGN Cost-effectiveness analysis using a Markov model. METHODS Using a Markov model, we estimated the incremental cost per quality-adjusted life-year (QALY) ...

PURPOSE The aim of this paper is to highlight the contributions that complementary efficacy, effectiveness, and cost-effectiveness studies can make to assessing the outcomes of assistive technology interventions for enhancing mobility. METHOD The terms, 'assistive technology outcomes research' and 'assistive technology interventions', are defined. Several bases are examined for the shortage o...

AIMS We examined the cost-effectiveness of extended smoking cessation treatment in older smokers. DESIGN Participants who completed a 12-week smoking cessation program were factorial randomized to extended cognitive behavioral treatment and extended nicotine replacement therapy. SETTING A free-standing smoking cessation clinic. PARTICIPANTS A total of 402 smokers aged 50 years and older w...

A retrospective survey, based on a standardized questionnaire sent to qualified public health experts in tuberculosis in 50 European countries, was carried out to evaluate the following: concordance between national vaccination programmes and WHO recommendations on BCG vaccination for prevention of tuberculosis; relation between BCG vaccination and revaccination policy and the tuberculosis epid...

Methods of economic evaluation, especially cost-effectiveness analysis and cost-benefit analysis, are widely used to examine new healthcare technologies. However, few economic evaluations of pharmacogenomics have been conducted, and pharmacogenomic researchers may be unfamiliar with how to review or conduct these analyses. This review provides an overview of the methods of economic evaluation a...

human papilloma virus (hpv) vaccine recently has been added to the iran drug list, decision makers need information beyond that available from rcts to recommend funding for this vaccination program to add it to the national immunization program in iran. modeling and economic studies have addressed some of those information needs in foreign countries. in order to determine the long term benefit ...

For more than twenty-five years software inspections have been considered an effective and efficient method for software quality improvement [3,4,9]. The goal of inspections is to detect defect before the testing stage begins. According to the data published in the literature, software design inspections save on average 44% of the defect detection costs, and code inspections save on average 39%...

Health policy instruments such as the public financing of health technologies (e.g., new drugs, vaccines) entail consequences in multiple domains. Fundamentally, public health policies aim at increasing the uptake of effective and efficient interventions and at subsequently leading to better health benefits (e.g., premature mortality and morbidity averted). In addition, public health policies c...