The National Institute for Health and Care Excellence (NICE), as part of the institute's single technology appraisal (STA) process, invited the manufacturer of pomalidomide (POM; Imnovid®, Celgene) to submit evidence regarding the clinical and cost effectiveness of the drug in combination with dexamethasone (POM + LoDEX) for the treatment of relapsed and refractory multiple myeloma (RRMM) after...

Immobilization of the chiral salen-metal complex [Mn(III)(salen)(H(2)O)(2)ClO(4)] on the Keggin-type polyoxometalate (POM) skeletons leads to the isolation of POM derivatives functionalized with chiral salen-metal complexes, which represent the first examples of introducing chiral salen-metal complexes into the POM systems.

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We have developed a variant of the pom-pom model that qualitatively describes two surprising features recently observed in filament stretching rheometer experiments of uniaxial extensional flow of industrial branched polymer resins: (i) Overshoots of the transient stress during steady flow and (ii) strongly accelerated stress relaxation upon cessation of the flow beyond the overshoot. Within th...

The authors report a rare case of primary orbital melanoma (POM) combined with giant divided nevus of the eyelid. An 8-year-old Chinese girl is referred for evaluation of 2-month duration of exophthalmos with decreased vision, epiphora, and pain on her right eye. His presentation, imaging, biopsy, histopathology, and management are presented. The possible cellular origin of the POM and the rela...

Odontogenic myxoma is an uncommon, benign neoplasm and originates exclusively from the toothbearing areas of the jaw and more commonly found centrally in the mandible. Soft-tissue localization is seldom seen and is categorized as peripheral odontogenic myxoma. (POM). POM has a low recurrence rate. It grows slowly and less aggressive as compared to the central variety. Only a few cases of POM lo...

The widespread use of triclosan (TCS) in household cleaning products, medical devices and personal care poses a potential risk to the ecological system and human health due to its release into sediments, surface water and ground water resources and chronicle toxicity to aquatic organisms. A novel molecularimprinted electrochemical sensor based on gold nanoparticles decorating polyoxometalate (H...

A unique approach was used in which polyoxometalate-based ionic liquids (POM-IL) were synthesized and employed for the one-pot dissolution and conversion of biomass. A library of four functional POM-IL compounds was synthesized using two cationic organic groups (1-butyl-3methylimidazolim and 1-ethyl-3-methylimidazolium) and two anionic POMs (phosphotungstate and tungstosilicate). The POM-IL com...

Polyoxymethylene (POM) is an engineering thermoplastic. Formaldehyde is the monomer unit of this polymer. Depolymeraization of POM occurs at 100 o C and yields formaldehyde whereas thermal degradation occurs at 270 o C. During thermal degradation, POM splits into carbon dioxide, water and formic acid. It has been proved that formaldehyde can be used as hydrogen source, when metallic nanoparticl...

Green-chemistry type procedures were used to synthesize Pd nanostructures encapsulated by a vanadium-substituted Wells-Dawson-type polyoxometalate (Pd@POM). The cyclic voltammogram run with the Pd@POM-modified glassy carbon electrode shows well-defined waves, associated with Pd nanostructures and the V/V redox couple. The Pd@POM-modified electrode displayed remarkably reproducible cyclic voltam...