INTRODUCTION Inconsistent results have been reported about the risk stratification of patients with Brugada syndrome. We have summarized the evidence regarding the strength of association between 6 risk factors (family history of sudden cardiac death [SCD] or syncope, inducible ventricular arrhythmias on electrophysiology study [EPS], spontaneous type 1 Brugada electrocardiogram [ECG], male sex...

The current study aimed to identify a comprehensive expression-profile of microRNAs (miRNAs) in expressed prostatic secretion (EPS) collected from healthy men and patients with CP/CPPS (Chronic prostatitis/Chronic pelvic pain syndrome). After clinical screening of 382 participants, 60 healthy men and 59 IIIA CP/CPPS patients with significant pelvic-pain were included into this study from March ...

Although the initiation, development and control of biofilms has been an area of experimental investigation for more than three decades, the role of extra-cellular polymeric substance (EPS) has not been well studied. We present a mathematical description of the EPS matrix to study the development of heterogeneous biofilm morphology. In developing the model, we assume that the biofilm is a biolo...

Small area ecological studies are commonly used in epidemiology to assess the impact of area level risk factors on health outcomes when data are only available in an aggregated form. However, the resulting estimates are often biased due to unmeasured confounders, which typically are not available from the standard administrative registries used for these studies. Extra information on confounder...

Organophosphate being the lethal compound and easily available insecticide in developing countries has significant potential health risk. The morbidity related to organophosphate poisoning as delayed peripheral neuropathy, extra pyramidal syndromes neuropsychiatric manifestations are still major consequences of secondary neuronal damage. Herein, we present a case 23 year old lady who ingested c...

Background/Aims Functional dyspepsia (FD) remains a great clinical challenge since the FD subtypes, defined by Rome III classification, still have heterogeneous pathogenesis. Previous studies have shown notable differences in visceral sensation processing in the CNS in FD compared to healthy subjects (HS). However, the role of CNS in the pathogenesis of each FD subtype has not been recognized. ...

Sir, Among the complications related to PD, the most serious and life-threatening one is encapsulating peritoneal sclerosis (EPS), with a reported mortality rate of more than 60% within 4 months of diagnosis w1±3x. The poor prognosis of EPS has had a negative impact on the acceptance of PD as an adequate alternative dialysis therapy to HD. This trend has been especially prominent in Japan where...

in this study, the neutral monosaccharide composition of the extracellular polysaccharide (eps), extracted from thermal bacillus, was determined by liquid chromatography-mass spectrometry and high performance liquid chromatography. our analysis indicated that the eps consisted of rhamnose, mannose, galactose, glucose, fructose, arabinose and xylose. in addition to the neutral sugars in the eps,...

cronkhite- canada syndrome (ccs) considered as a rare and non-hereditary disorder. gastrointestinal polyposis and diarrhea along with some extra signs and symptoms such as hypoproteinemia, and epidermal manifestations are recognized in this syndrome. the pathophysiology of this syndrome is not completely understood and it seems that inflammatory processes may be involved. we present a 50 year-o...

L-Dopa and amantadine hydrochloride were separately given to patients with diverse extra-pyramidal disorders including progressive supranuclear palsy; porto-systemic encephalopathy; oculogyric crises; drug-induced Parkinsonism; Huntington's chorea, hemiballismus; spasmodic torticollis, familial tremor; and athetosis. Akinesia and rigidity were improved in the first two conditions and simultaneo...