background: heavy metals tend to bioaccumulate in living organisms, and their accumulation has been a major concern. as mammals are known to excrete heavy metals via their bile, it seems to be very promising to analyse metal burdens of par-asites that infect the biliary tree such as liver flukes of the genus fasciola . the pre-sent study was carried out to evaluate f. hepatica and f. gigantica ...

In this study, the rabbit was assessed as a laboratory host for the helminthes parasite, Fasciola gigantica. Three groups of rabbits were Infected experimentally with 5, 10 end 15 metacercariae of F. gigantica respectively. Clinical signs found included pale mucous membrane, progressive emaciation and rough hair coat. The post mortem findings Included haemorrhage and scattered calcified nodules...

Fascioliasis is a common parasitic disease in livestock in China. However, human fascioliasis is rarely reported in the country. Here we describe an outbreak of human fascioliasis in Yunnan province. We reviewed the complete clinical records of 29 patients and performed an epidemiological investigation on the general human population and animals in the outbreak locality. Our findings support an...

The digenetic trematode Fasciola gigantica is a parasite of great agricultural and economic importance. Along with Fasciola hepatica, F. gigantica incurs huge economic losses to the agricultural sector. Because of unavailability of an effective and commercial vaccine, the earliest diagnosis of the disease is the only way to control the disease. The conventional coprological techniques are able ...

background: fasciola species are parasitic trematode with world wide distribution that infects wild and domesticated herbivores, particularly ruminants. the aim of the present study was to investigate the intra species variations of f. gigantica, from goats and buffalos isolates in two common geographic climates of iran. methods: fasciola species were collected from goat, buffalo, sheep, and ca...

Fasciolosis caused by Fasciola gigantica is a neglected tropical disease but a constraint on the growth and productivity of cattle, buffaloes and sheep in the tropical countries of Asia and Africa. Resistance to commonly used anthelmintics in Fasciola has increased the need to search for alternative therapeutic targets. RNA interference is the current tool of choice in the search for such targe...

Development and evaluation of a single step duplex PCR for simultaneous 1 detection of Fasciola hepatica and Fasciola gigantica 2 (Fasciolidae; Trematoda; Platyhelminthes) 3 Thanh Hoa Le, Khue Thi Nguyen, Nga Thi Bich Nguyen, Huong Thi Thanh Doan, 4 Xuyen Thi Kim Le, Chau Thi Minh Hoang, and Nguyen Van De 5 Department of Immunology, Institute of Biotechnology, Vietnam Academy of Science and 6 T...

This study aims to determine the anthelmintic activity ethanol extract of porang tubers (A. oncophillus) against F. gigantica worms in vitro. There were five treatments and each treatment was done replications used 10 gigantica. The this research K- with CMC Na 1%, K+ Albendazole 2.4 mg/ml, P1 concentration 5%, P2 10%, P3 20%. results showed that Porang tuber had an effect In a 20%, there prope...

background: we evaluated the genetic diversity of samples identified morphologically as fasciola spp. from sheep, cattle and goat from kermanshah province, western iran using pcr-rflp method. methods: we used pcr-rflp analysis of ribosomal its1 fragment using rsai restriction enzyme to investigate the genetic characteristics of fasciola species obtained from different hosts (16 sheep, 28 cattle,...

In this study, monoclonal antibodies were developed from the partially purified surface tegumental antigens of F. gigantica. Nine MoAbs: 2G11, 1G2, 1B12, 2G2, 2G5, 3C6, 3G2, 3G3 and 3F6 were used for anatomical localization of adult F. gigantica. The reaction was demonstrated by Avidin-Biotin method. The results revealed that among the sections stained with non-immune sera and control group, th...