نتایج جستجو برای: f hepatica

تعداد نتایج: 307078  

Journal: :Folia biologica 2013
Lidia Kołodziejczyk Iwona Jarocka Elzbieta Skrzydlewska

Fasciola hepatica infection results in increased production of reactive oxygen species (ROS) and changes the activity/level of antioxidants in the host organism, which leads to oxidative stress formation and oxidative modifications of lipids and proteins. Taking this into account, the aim of this study was to assess the antioxidant potential and the activity of proteases and their inhibitors in...

Journal: :Journal of immunology 2009
Kevin P Walsh Miriam T Brady Conor M Finlay Louis Boon Kingston H G Mills

The lower incidence of allergy and autoimmune diseases in developing countries has been associated with a high prevalence of parasitic infections. Here we provide direct experimental evidence that parasites can exert bystander immunosuppression of pathogenic T cells that mediate autoimmune diseases. Infection of mice with Fasciola hepatica resulted in recruitment of dendritic cells, macrophages...

2015
Adam Novobilský Johan Höglund

Control of Fasciola hepatica infection in livestock is based on annual treatment using flukicides such as triclabendazole, albendazole and closantel. However, triclabendazole resistant F. hepatica populations are emerging worldwide and resistance is emerging to albendazole, whereas it has until now never been described for closantel. In Sweden, a topical formulation containing a combination of ...

2017
Samantha N McNulty Jose F Tort Gabriel Rinaldi Kerstin Fischer Bruce A Rosa Pablo Smircich Santiago Fontenla Young-Jun Choi Rahul Tyagi Kymberlie Hallsworth-Pepin Victoria H Mann Lakshmi Kammili Patricia S Latham Nicolas Dell'Oca Fernanda Dominguez Carlos Carmona Peter U Fischer Paul J Brindley Makedonka Mitreva

Food borne trematodes (FBTs) are an assemblage of platyhelminth parasites transmitted through the food chain, four of which are recognized as neglected tropical diseases (NTDs). Fascioliasis stands out among the other NTDs due to its broad and significant impact on both human and animal health, as Fasciola sp., are also considered major pathogens of domesticated ruminants. Here we present a ref...

Journal: :Infection and immunity 2006
Daricel Torres Ana M Espino

FhSAP-2 is a novel member of the Fasciola hepatica saposin-like protein family that induces protection in rabbits against a challenge infection. We investigated the presence of lineal B-cell epitopes within this protein using a set of overlapping synthetic peptides. Peptides were tested in enzyme-linked immunosorbent assays against sera from rabbits infected with F. hepatica. Two dominant epito...

Journal: :Geospatial health 2015
Antonio Bosco Laura Rinaldi Vincenzo Musella Alessandra Amadesi Giuseppe Cringoli

The objective of the present study was to investigate whether climate change in recent years have influenced the onset of acute outbreaks of Fasciola hepatica in ovine farms in southern Italy. In May-June 2014, a severe outbreak of F. hepatica occurred in three sheep farms in the Campania region. Clinical, coprological and necroscopic examinations were performed. Morbidity and mortality due to ...

Journal: :Veterinary parasitology 2003
J De Bont E Claerebout G Riveau A M Schacht K Smets G Conder D A Brake A Capron J Vercruysse

The potential of a recombinant Schistosoma bovis 28-kDa glutathione S-transferase (rSb28GST) to protect cattle against Fasciola hepatica was tested in a vaccination trial. Thirty two calves were randomly divided into four groups of eight animals. Calves of the three vaccine groups received two intramuscular injections at 3 weeks interval, of 0.250mg rSb28GST in either aluminium hydroxide (Al(OH...

Journal: :Turkiye parazitolojii dergisi 2011
Nermin Sakru Metin Korkmaz Mustafa Demirci Aydınten Kuman Ulgen Zeki Ok

OBJECTIVE Fasciola hepatica, a liver fluke of sheep and cattle, may accidentally infect humans. The main signs and symptoms of the fasciolosis are eosinophilia, abdominal pain and hepatomegaly and may also be attributed to Cystic Echinococcosis (CE) caused by Echinococcus granulosus, which is a prevalent infection in Turkey. METHODS Sera samples of 226 CE suspected cases were tested for anti-...

Journal: :Veterinary parasitology 2011
L Ai Y B Weng H M Elsheikha G H Zhao S Alasaad J X Chen J Li H L Li C R Wang M X Chen R Q Lin X Q Zhu

The present study examined sequence variability in a portion of the mitochondrial cytochrome c oxidase subunit 1 (pcox1) and NADH dehydrogenase subunits 4 and 5 (pnad4 and pnad5) among 39 isolates of Fasciola spp., from different hosts from China, Niger, France, the United States of America, and Spain; and their phylogenetic relationships were re-constructed. Intra-species sequence variations w...

Journal: :Molecular & cellular proteomics : MCP 2007
Russell M Morphew Hazel A Wright E James LaCourse Debra J Woods Peter M Brophy

Livestock infection by the parasitic fluke Fasciola hepatica causes major economic losses worldwide. The excretory-secretory (ES) products produced by F. hepatica are key players in understanding the host-parasite interaction and offer targets for chemo- and immunotherapy. For the first time, subproteomics has been used to compare ES products produced by adult F. hepatica in vivo, within ovine ...

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