BACKGROUND Few studies have investigated predictors of discordance between liver biopsy (LB) and liver stiffness measurement (LSM) using FibroScan®. We assessed predictors of discordance between LB and LSM in chronic hepatitis B (CHB) and investigated the effects of necroinflammatory activity. METHODS In total, 150 patients (107 men, 43 women) were prospectively enrolled. Only LSM with ≥ 10 v...

In the paper, possibility of Appell hypergeometric function F4(1,2;2,2;z1,z2) approximation by a branched continued fraction special form is analysed. The correspondence constructed to F4 proved. convergence obtained in some polycircular domain two-dimensional complex space established, and numerical experiments are carried out. results calculations confirmed efficiency approximating illustrate...

We have estimated the macrophage content of different tissues of the normal adult mouse using F4/80, a highly specific antigen marker for mature mouse macrophages. An absorption indirect binding assay was used to quantitate F4/80 antigen against a calibration standard made from the J774.2 macrophage-like cell line. The richest sources of tissue F4/80 antigen were found to be bone marrow, spleen...

We study s-extremal codes over F4 or over F2. A Type I self-dual code over F4 or over F2 of length n and minimum distance d is s-extremal if the minimum weight of its shadow is largest possible. The purpose of this paper is to give some results which are missing in a series of papers by Bachoc and Gaborit [2], by Gaborit [6], and by Bautista, et. al. [1]. In particular, we give an explicit form...

OBJECTIVE The aim of this study was to investigate liver fibrosis using non-invasive Real-time Tissue Elastography (RTE) and transient elastography (FibroScan) methods. METHODS RTE, FibroScan and percutaneous liver biopsy were all performed on patients with chronic liver disease, particularly hepatitis C, to investigate liver fibrosis. RESULTS FibroScan and RTE were compared for fibrous liv...

Mutations in the parkin gene are the major cause of early-onset familial Parkinson's disease (PD). We previously reported the generation and analysis of a knockout mouse carrying a deletion of exon 3 in the parkin gene. F1 hybrid pa+/- mice were backcrossed to wild-type C57Bl/6 for three more generations to establish a pa-/-(F4) mouse line. The appearance of tyrosine hydroxylase-positive neuron...

With the purpose to elucidate further the properties of the supernatant F4 obtained by centrifugation at 100, 000 g from the regional lymph node cells of the Cb mice sensitized with EHRLICH ascites tumor cells, the supernatant (cf. Report 13) was subjected to the following treatments:. The supernatant (F4) was first diluted variously with Hanks solution. 2. F4 was passed through Seitz filter. 3...

The F4 idiotype is a heavy chain determinant expressed almost exclusively on IgG immunoglobulins and is highly associated with specificity for double-stranded DNA. Since high-titered F4 expression is present predominantly in sera of patients with systemic lupus erythematosus (SLE), we thought F4+ IgG antibodies might constitute a useful subset of immunoglobulins in which to investigate lupus-sp...

The macrophage-specific antigen F4/80 has been localized in mouse lymphoid and hematopoietic tissue and skin using immunoperoxidase staining. The antigen permits identification of early mononuclear phagocyte precursors in the bone marrow, and is present also on larger cells forming the center of hematopoietic islands and lining vascular sinuses. In thymus F4/80+ cells are numerous in both corte...