I read with great interest the article by Strand et al. The aim of the study was to assess the effects of belimumab treatment plus standard systemic lupus erythematosus (SLE) therapy on health-related quality of life in patients with active, autoantibody-positive SLE. Of particular interest are the results about the impact of belimumab on fatigue scores. Fatigue is a common complaint of patient...

Introduction Fatigue in Parkinson’s Disease (PD) remains poorly understood. The comprovation derives from and is proven by psychometric scales. objective to prepare a Technical Scientific Report on the performance of scales PD. Methods Based Methodological Guideline for Preparation Report, Brazil 2014, we conducted search MEDLINE / PubMed, Virtual Health Library (BVS) Cochrane, then review crit...

The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with endothelium. Its transparency is the result of the regular spacing of collagen fibers with remarkably uniform diameter and interfibrillar space. Cornea...

Little is known about the effects of spiritual care training for professionals in palliative medicine. We therefore investigated prospectively the effects of such training over a six-month period. All 63 participants of the three and a half-day training were asked to fill out three questionnaires: before and after the training, as well as six months later. The questionnaires included demographi...

Background: Fatigue is a common symptom in many chronic inflammatory diseases, including rheumatoid arthritis (RA). It considered one of the most frustrating, uncontrollable, and overwhelming symptoms. However, rheumatologists do not assess fatigue despite its clinical significance impact on patients’ lives. Objectives: The aims this study were to determine whether RA patients express more than...

The naturally occurring polyphenol, resveratrol (RSV), is known for a broad range of actions. These include a positive impact on lifespan and health, but also pro-apoptotic anti-cancer properties. Interestingly, cell culture experiments have revealed a strong impact of RSV on mitochondrial function. The compound was demonstrated to affect mitochondrial respiration, structure and mass of mitocho...

Cancer-related fatigue can continue long after curative cancer treatment. The aim of this study was to investigate sleep and rest–activity cycles in fatigued non-fatigued survivors. We hypothesized that would be more disturbed people experiencing clinically-relevant fatigue, objective measures associated with the severity Cancer survivors (n = 87) completed a 14-day wrist actigraphy measurement...

BACKGROUND AND AIM Fatigue is a common and bothersome symptom in inflammatory bowel disease (IBD) patients. The study was aimed to determine the relationship of biological and psychological factors with IBD-related fatigue. METHODS Consecutive clinically inactive IBD outpatients receiving immunosuppressants or biological drugs were enrolled between January and December 2013. Patients complete...

PURPOSE/OBJECTIVES To describe the symptom concerns of patients with hepatocellular carcinoma (HCC) and pancreatic cancer and explore the effect of symptoms on patients' quality of life (QOL). DESIGN Descriptive, longitudinal study. SETTING Ambulatory clinics of a comprehensive cancer center. SAMPLE 45 patients actively receiving treatment for either HCC or pancreatic cancer. METHODS Pa...

GOALS: The aims of this study were to evaluate the treatment efficacy of the structured life review interviews and the Short-Term Life Review on the spiritual well-being of terminally ill cancer patients, in order to improve patients’ quality of life. SUBJECTS and METHODS: Participants were patients in palliative care units in Japan. In the study 1, the structured life review interviews were co...