نتایج جستجو برای: fatty acid synthase

تعداد نتایج: 864452  

Journal: :Reviews of reproduction 2000
R Mattos C R Staples W W Thatcher

Fats in the diet can influence reproduction positively by altering both ovarian follicle and corpus luteum function via improved energy status and by increasing precursors for the synthesis of reproductive hormones such as steroids and prostaglandins. Dietary fatty acids of the n-3 family reduce ovarian and endometrial synthesis of prostaglandin F2alpha, decrease ovulation rate in rats and dela...

Journal: :Journal of Biological Chemistry 2005

Journal: :Proceedings of the National Academy of Sciences 1995

2017
Pei Lin Jian-Mei Lu Yan-Fang Wang Wen Gu Rong-Hua Zhao Jie Yu

AIM 2,3,5,4'-Tetrahydroxy-stilbene-2-O-β-d-glucoside (TSG), a natural stilbene, shows great activities in hepatic lipid regulation, especially for hepatic triglyceride lowering. However, information about its mechanisms on biosynthesis and degradation of triglyceride is still limited. This research pays close attention to clarify the mechanism of TSG on prevention of hepatic lipid accumulation....

Journal: :Cancer research 2013
Kevin J Williams Joseph P Argus Yue Zhu Moses Q Wilks Beth N Marbois Autumn G York Yoko Kidani Alexandra L Pourzia David Akhavan Dominique N Lisiero Evangelia Komisopoulou Amy H Henkin Horacio Soto Brian T Chamberlain Laurent Vergnes Michael E Jung Jorge Z Torres Linda M Liau Heather R Christofk Robert M Prins Paul S Mischel Karen Reue Thomas G Graeber Steven J Bensinger

The sterol regulatory element-binding proteins (SREBP) are key transcriptional regulators of lipid metabolism and cellular growth. It has been proposed that SREBP signaling regulates cellular growth through its ability to drive lipid biosynthesis. Unexpectedly, we find that loss of SREBP activity inhibits cancer cell growth and viability by uncoupling fatty acid synthesis from desaturation. Int...

Journal: :American Journal of Clinical Pathology 2006

1997
NORVIN D. FERNANDES

Methyl-branched fatty acids and polyketides occur in a variety of living organisms. Previous studies have established that multifunctional enzymes use methylmalonyl coenzyme A (CoA) as the substrate to generate methyl-branched products such as mycocerosic acids and polyketides. However, we do not know which of the component activities show selectivity for methylmalonyl-CoA in any biological sys...

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