UNLABELLED Folic acid was linked regioselectively through its alpha- and gamma-carboxyl groups to 4-fluorobenzylamine (FBA), and the alpha- and gamma-FBA-folate regioisomers were evaluated for their ability to bind to folate receptor-positive cells. The 18F-labeled alpha/gamma-FBA-folate counterpart was examined for in vivo tumor targeting efficiency in nude mice bearing folate receptor-positiv...

Recent reports of a high response to bodies in the fusiform face area (FFA) challenge the idea that the FFA is exclusively selective for face stimuli. We examined this claim by conducting a functional magnetic resonance imaging experiment at both standard (3.125! 3.125! 4.0 mm) and high resolution (1.4! 1.4! 2.0 mm). In both experiments, regions of interest (ROIs) were defined using data from b...

Recent reports of a high response to bodies in the fusiform face area (FFA) challenge the idea that the FFA is exclusively selective for face stimuli. We examined this claim by conducting a functional magnetic resonance imaging experiment at both standard (3.125 x 3.125 x 4.0 mm) and high resolution (1.4 x 1.4 x 2.0 mm). In both experiments, regions of interest (ROIs) were defined using data fr...

Introduction: Foreign body aspiration (FBA) is rare in adults and its clinical presentation can be very diverse. Acute symptoms as dyspnea and choking are often immediately linked to FBA. However, mild or even asymptomatic chronic pulmonary symptoms can be presented as a result of FBA. Physical examination is usually nonspecific. Chest X-ray is often normal or shows nonspecific findings. Treatm...

Flux balance analysis (FBA) is a standard optimization model that is used to study the metabolisms of cells that are in a steady state of optimal growth. The model optimizes a biologically defined objective while assuming (1) equilibria of a linear system of ordinary differential equations, and (2) deterministic data. However, the steady state assumption is imperfect from a biological point of ...

Abstract This paper presents a parameter free approach to identify the importance of reactions (and involved species) in biochemical reaction networks for purpose model order reduction. The new methodology is based on structure network assuming that at steady state flux distribution preserved. Our method employs Flux Balance Analysis (FBA) calculate these distributions. ranking comparison FBA r...

Flux balance analysis (FBA) determines theoretical capabilities of metabolic networks using only stoichiometry and fundamental physiochemical capacity constraints. Metabolic networks reconstructed from annotated genome and literature. Capacity constraints include maximum uptake rates of oxygen and substrates such as glucose, acetate, and lactose. FBA determines optimal flux distribution for giv...

We present a novel Facial Motion Cloning method relying on the combination of the radial basis functions (RBF) based scattered data interpolation with the encoding capabilities of the MPEG-4 Facial and Body Animation (FBA) international standard. Beside from an initial manual selection of feature points, our method works fully automatically without user interaction. The produced talking head is...