background: genital chlamydia infection (gci) and the associated pathologies have been implicated in tubal infertility. though the actual pathologic mechanisms are still uncertain, oxidative stress and other factors have been implicated. the purpose of the study was to determine the possible contribution of female reproductive hormones and biomarkers of oxidative stress in genital chlamydial in...

THE AIM OF THE STUDY The aim of the study was to determine menopause-related changes in serum levels of main proinflammatory and anti-inflammatory cytokines. MATERIAL AND METHODS The study included 175 women, who were divided into 5 study groups (group 1 - fertile women; group 2 - pre- and perimenopausal women; group 3 - postmenopausal women; group 4 - surgically induced menopausal women; gro...

Anti-zona-pellucida autoantibodies (AZP-Ab) and anti-sperm isoantibodies (ASA) were assessed in the cervical secretions from 73 infertile Jordanian women and 41 fertile control women using latex agglutination. Significantly more women with infertility had AZP-Ab and ASA (16.4% and 8.2% respectively) compared with fertile women (9.4% and 0%), with no relation to the etiology of infertility. Usin...

BACKGROUND With an increase in the number of putative inclusion membrane proteins (incs) in chlamydial genomes, there is a need for understanding their contribution in host-pathogen interactions. Thus in this study we determined the host mucosal and peripheral immune responses to incs (IncB and IncC) of Chlamydia trachomatis (CT). METHODS Female patients (n = 296) attending the gynaecology ou...

OBJECTIVE To assess the risk of borderline ovarian cancer among infertile women treated with fertility drugs. DESIGN Case-control study. SETTING Nationwide data obtained from public registers and postal questionnaires. PATIENT(S) All Danish women <60 years old with borderline ovarian cancer during the period 1989-1994 and randomly selected population controls. The analysis included 231 ca...

BACKGROUND Vascular endothelial growth factor (VEGF) is known to play a pivotal role in the development of endometriosis. This study was performed to investigate whether the VEGF gene 5'-untranslated region polymorphism is associated with susceptibility to advanced stage endometriosis. METHODS This study comprised 215 women with advanced stage endometriosis, 219 control women without endometr...

BACKGROUND Endometrial receptivity plays a key role in the establishment of successful implantation and its impairment may contribute to subfertility and limit the assisted reproduction techniques (ART) success. OBJECTIVE The aim of present study was to investigate endometrial receptivity in terms of β3 integrin, calcitonin and plexin-B1 expression in women with unexplained infertility. MAT...

abstract background: nitric oxide (no) is a molecule that incorporates in many physiological processes of female reproductive system. recent studies suggested the possible role of endothelial isoform of nitric oxide synthase (enos) enzyme in female infertility. objective: the aim of this study is to evaluate the expression of endothelial nitric oxide synthase in endometrial tissue of women with...