BACKGROUND AND OBJECTIVES Acinetobacter spp. are important causes of nosocomial infections. They possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (ESBLs). The aim of this study was to determine antibiotic resistance profile of Acinetobacter clinical isolates especially among ESBL-producing strains and to investigate the antimicrobial effects of oleo-g...

OBJECTIVES Ferula gummosa Boiss is native to central Asia. This plant has traditionally been used in the treatment of many diseases. The antihypoxic and antioxidant activities of Ferula gummosa roots were investigated. MATERIAL AND METHODS 1,1-diphenyl-2-picryl hydrazyl radical (DPPH), nitric oxide and hydrogen peroxide scavenging activities, Fe2+ chelating ability, reducing power and hemoglo...

Background and objectives: Ferula assa-foetida (asafoetida) is a native Iranian species which grows in different regions and climates in Iran. The plant is well known in Iranian Traditional Medicine as well as folk medicine for treatment of diseases. Several studies have been carried out on the essential oil of this species collected from different areas of Iran. This study is the first report ...

dormancy breaking and germination requirements were investigated in seeds of ferula ovina and ferula gummosa. seeds of rather species were collected from north and eastern-north rangelands of iran. seeds of each of the species were subjected to different treatments including various levels of ga3, chilling and combination of ga3 and chilling (ga-chilling). in contrast to treated seeds, non-trea...

OBJECTIVES The usage of medicinal plants as natural antimicrobial agents has grown in many fields including dental medicine. The aim of this in vitro study was three-fold: (i) to determine the chemical compositions of the Ferula gummosa essential oil (FGEO), (ii) to compare the antimicrobial efficacy of the oil with sodium hypochlorite (NaOCl) and chlorhexidine (CHX), (iii) to assess the toxic ...

The current research was performed aiming to investigate the effects of Ferula ovina essential oil on the fourth instar larval hemogram of Sesamia cretica. Four main sorts of circulating hemocytes, including prohemocytes, plasmatocytes, granulocytes (GRs), and oenocytoides, were identified in the fourth instar larvae. Treatment of the larvae with the concentration of 1000 ppm of the essential o...

Natural products and dietary components have earlier been proven as potential chemoprotective agents, and continuous efforts are in progress to search for such new products. Gentamicin, an aminoglycoside antibiotic, is widely used for treating the infections caused by many gram negative bacteria. However, besides other unwanted effects, the drug causes tubular cell necrosis in the proximal conv...

OBJECTIVE The genus of Ferula belongs to the tribe Peucedaneae, subfamily of Apioideae and family of Umbelliferae with 133 species distributed throughout the Mediterranean area and central Asia, especially in the former USSR and neighboring countries such as Iran. The popular Persian name of the most of these species is "Koma". In this research we tried to isolate and elucidate the structure of...

In this study we investigated the phytoconstituents Calluna vulgaris, Ferula hermonis and Tribulus terrestris, and then assessed their possible biological activities by using standard methods. A preliminary phytochemical investigation of the three extracts revealed the presence of alkaloids, flavonoids, proteins, lipids, phenolic compounds, saponins, sterols and amino acids. Three extracts show...

Background and Objective: To assess the control release of bio-molluscicides (Crude Ferula asafoetida and their active component ferulic acid) loaded in alginates as binding matrix. Methodology: Sodium alginate, an anionic block copolymer of β-D-mannuronic acid and α-L-guluronic acid, is a readily available, non-toxic polysaccharide its property to form gel with divalent and multivalent cations...