Chromosomal mosaicism is one of the primary interpretative issues in prenatal diagnosis. In this review, the mechanisms underlying feto-placental chromosomal mosaicism are presented. Based on the substantial retrospective diagnostic experience with chorionic villi samples (CVS) of a prenatal diagnosis laboratory the following items are discussed: (i) The frequency of the different types of mosa...

Congenital diaphragmatic hernia (CDH) may be isolated or associated with other structural anomalies, the latter with poor prognosis. The defect allows viscera to herniate through the defect into the chest, competing for space with the developing lungs. At birth, pulmonary hypoplasia leads to respiratory insufficiency and persistent pulmonary hypertension that is lethal in up to 30% of patients....

Revista Científica da Ordem dos Médicos www.actamedicaportuguesa.com 137 gemelar em que há uma mola hidatiforme completa e um feto viável, o casal tem de optar entre interromper a gravidez de um feto vivo, sem patologia, ou deixar prosseguir a gestação, enfrentando os riscos de morte fetal e de complicações maternas graves. Se o casal optar por prosseguir a gravidez, a grávida deve ser referenc...

INTRODUCTION Abdominal pregnancy, a rare diagnosis, belongs to the ectopic pregnancy group, the leading cause of pregnancy related exitus. The positive diagnosis is very difficult to establish most often in an acute setting, leading to a staggering percent of feto-maternal morbidity and mortality. CASE REPORT We present the case of 26-weeks-old abdominal pregnancy with partial feto-placental ...

A complete mole coexisting with dichorionic twins was diagnosed by the combined use of sonography and chorionic villus sampling at 10 weeks gestation. The pregnancy resulted in the death of one fetus at 31 weeks from presumed feto-maternal haemorrhage, while the other fetus survived in good condition. A summary of the available literature, combined with this report, reveals a total of seven pre...

Aplastic anaemia occurring in pregnancy is a rare event with life threatening challenges for both mother and child. We present a successful fetomaternal outcome despite the challenges in the management of this rare condition in a tertiary but resource poor centre. This is case of a 37 year old Nigerian woman G6P0+5managed with repeated blood transfusions from 28 weeks of gestation for bone marr...

Introduction: Abruptio Placenta is a major cause of maternal morbidity and perinatal mortality globally and is of serious concern in the developing world. Materials and methods: A retrospective cohort study was designed and carried out between January and December 2015 in the Institute of Maternal and Child Health (IMCH) attached to GMC, Calicut. Results: We evaluated 140 cases of abruptio plac...

Maternal-fetal cellular trafficking (MFCT) is a well described phenomenon during pregnancy in which maternal cells migrate into the fetus and fetal cells migrate into the mother [1–5]. The specific mechanisms leading to such trafficking and its lifelong consequences have fascinated scientists for decades and are still actively being investigated. For example, several groups have demonstrated an...