objective: acute mesenteric ischemia (ima) is a vascular emergency with broad variability of clinical presentations and non-specific laboratory findings. therefore, there is a significant need for reliable serological markers of ischemia. various laboratory studies may be performed for suspected ami, but in general, such studies will not establish the diagnosis. methods: in a prospective, non-i...

Biomaterial Fibrin Clot Structures Stylized fibrin clots are presented in article number 2100988 by Anna Waterhouse and co-workers. Less dense on hydrophobic (right) compared to hydrophilic (left) polystyrene more easily lysed, demonstrating potential for targeted fibrinolytic treatment improved hemocompatible device design.

Background: In recent years, transplantation of cryopreserved ovarian tissue has proved to be a promising approach to restore fertility in cancer patients. However, such a procedure cannot be carried out in women at risk of ovarian involvement due to the threat of reintroducing malignant cells. The aim of this study was therefore to create an artificial ovary as an alternative to restore fertil...

Abnormal fibrin architecture is thought to be a determinant factor of hypofibrinolysis. However, because of the lack of structural knowledge of the process of fibrin digestion, relationships between fibrin architecture and hypofibrinolysis remain controversial. To elucidate further structural and dynamic changes occurring during fibrinolysis, cross-linked plasma fibrin was labeled with colloida...

injection molding is one of the most common processes which are used for manufacturing different plastic parts. this method includes 3 continuous steps: filling of the mold, cooling and driving the part out. a wide range of plastic and non-plastic materials can be used as raw material in this process. one of the most important advantages of this way of production is that it is very economic. in...

Thrombus fragmentation during endovascular stroke treatment, such as mechanical thrombectomy, leads to downstream emboli, resulting in poor clinical outcomes. Clinical studies suggest that risk is dependent on clot composition. This current study presents the first experimental characterization of composition-dependent fracture properties blood clots, addition development a predictive model for...

The fibrin polymers formed in solution during the earliest phase of the fibrinogen-fibrin conversion are shown to be stable soluble molecules at pH7.4 and 0.15m- or 0.3m-NaCl. The various sequential soluble fibrin polymers produced from the fibrinogen-thrombin reaction can be observed by gel chromatography and can be isolated for characterization. The mechanism of fibrin polymerization proposed...

Samples of normal and atherosclerotic vessels obtained from vascular and cardiothoracic surgery were examined for the distribution of fibrinogen/fibrin I, fibrin II, and fibrin(ogen) degradation products (Fragment D/DD) by using recently characterized monoclonal antibodies that recognize and distinguish the three molecular forms (MAbs 18C6, T2G1, and GC4, respectively) with the ABC-immunoperoxi...

Brass Ferrules have been used as packing in a laboratory- scale glass distillation column approaching pilot plant size because of their availability in all sizes and low cost. The available size range is such that these ferrules could also be used in industry and the results of this study could be scaled up. The performance of the new packing has been compared with the performance of glass ...