OBJECTIVE To estimate mercury intake due to fish consumption among the individuals from Gipuzkoa participating in the European Prospective Investigation into Cancer (EPIC), and to validate the estimation of mercury exposure through diet, by measuring blood mercury level. DESIGN AND SETTING The population for the EPIC Gipuzkoa cohort was recruited from 1992 to 1995. Each individual's diet was ...

OBJECTIVE Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects. DESIGN A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were used to assess the possible dose-response relationship. Subgroup analyses wer...

Objective. To examine the association between fish and marine long-chain omega-3 polyunsaturated fatty acid (LC n-3 PUFA) consumption and incidence of type 2 diabetes (T2D) in prospective cohort studies. Methods. Meta-analytic procedures were used to estimate the relative risk (RR) using random effects or fixed effects generic inverse variance model. Publication bias and study heterogeneity wer...

Eicosapentaenoic acid (EPA), which predominates in marine fish, tends to counteract and inhibit the uptake and incorporation of arachidonic acid and membrane phospholipids and dilute arachidonic acid as a potential substrate for oxidation. Thus, fish intake may be protective for the occurrence of asthma and other pulmonary diseases. We wanted to examine the relationship between the effect of ch...

BACKGROUND Low intake of fish, polyunsaturated fatty acids (PUFA) and vitamin D deficiency has been suggested to play a role in the development of schizophrenia. Our aim was to evaluate the association between the intake of different fish species, PUFA and vitamin D and the prevalence of psychotic-like symptoms in a population-based study among Swedish women. METHODS Dietary intake was estima...

AIMS To study the effect of fish consumption on the risk of acute coronary syndrome (ACS) in healthy subjects. METHODS AND RESULTS This Danish follow-up study included 57,053 men and women between 50 and 64 years. Intake of lean and fatty fish was estimated from a detailed and validated food frequency questionnaire. Potential cases of ACS were identified through nationwide medical databases. ...

BACKGROUND The relation between dietary fish intake and brachial artery measures, including brachial artery flow-mediated dilation (FMD), has not been well established across sex and racial-ethnic groups. OBJECTIVE We hypothesized that consumption of nonfried fish and plasma phospholipid measures of long-chain omega-3 (n-3) fatty acids would be positively associated with larger FMD in men and...

BACKGROUND Once- or twice-weekly consumption of fish (or a small amount of fish intake) reduces the risk of coronary heart disease and sudden cardiac death in Western countries. It is uncertain whether a high frequency or large amount of fish intake, as is the case in Japan, further reduces the risk. METHODS AND RESULTS To examine an association between high intake of fish and n3 polyunsatura...

Background—Onceor twice-weekly consumption of fish (or a small amount of fish intake) reduces the risk of coronary heart disease and sudden cardiac death in Western countries. It is uncertain whether a high frequency or large amount of fish intake, as is the case in Japan, further reduces the risk. Methods and Results—To examine an association between high intake of fish and n3 polyunsaturated ...

OBJECTIVES Fish is rich in nutrients that are favorable to bone health, but limited data are available regarding the relationship between fish intake and hip fractures. Our study examined the association between habitual fish intake and risk of hip fractures. METHODS A case-control study was performed between June 2009 and June 2012 in Guangdong Province, China. Five hundred and eighty-one hi...