An oral sustained-release floating tablet formulation of metformin HCl was designed and developed. Effervescence and swelling properties were attributed on the developed tablets by sodium bicarbonate and HPMC-PEO polymer combination, respectively. Tablet composition was optimized by response surface methodology (RSM). Seventeen (17) trial formulations were analyzed according to Box-Behnken desi...

This paper focuses on how leaders in Japan, Russia, and Western countries talk about the “war on terrorism.” The paper discusses the difficulties of defining “terrorism,” because, unlike Marxism or capitalism, “terrorism” is not an ideology. Instead the term may be used to designate actions that are used by members of non-governmental organizations against civilian targets. In the case of the “...

In times of transition and transformation, legal images metastasize. This idea can be usefully related both to Winnicott’s theory of transitional objects and Barthes’ theory of myth. But each tell only part of the full story. Barthes fails to fully account for the stabilizing effect of the reassuring signifier; Winnicott fails to fully account for the ideological adaptability – and implications...

BACKGROUND It is easy to forget about the real human experience when faced with the pressure of output measurement, organizational change, and large-scale statistical studies. This article takes a different perspective and provides a glimpse into one man's life to show the many relationships that can be involved when someone is ill. METHODS The information in this paper is based on interviews...

The present study examined whether automaticity, defined here as independence from attentional modulation, is a fundamental principle of the neural systems specialized for processing social signals of environmental threat. Attention was focused on either scenes or faces presented in a single overlapping display. Facial expressions were neutral, fearful, or disgusted. Amygdala responses to facia...

This paper aims to apply Derridean deconstructionism Anton Chekov's The CherryOrchard explore the emergence of new possibilities in in-between space due loss Transcendental signifiers and reversal binary roles. Derrida presents a universe wherein Signifier is lost, world freed binaries-based signification system.Consequently, area between binaries becomes where polarity disintegrates. suggests ...

The main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of Methocel® K15, Ethocel® standard 7FP premium, Eudragit ® RS100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. Risperidone floating tablets were formulated by wet granulati...

With the aim of extending the use of integrated variational principles on fluid and deckplate to the large deflection analysis of floating roofs, this paper investigates the significance of theflexural and membrane components in the formulations of the deck plate. Applying integratedvariational principles on deck plate and fluid facilitate the treatment of the compatibility ofdeformation betwee...