Purpose: Phosphatidylinositol 3V-kinase (PI3V-kinase) can be activated by the K1protein of Kaposi sarcoma ^ associated herpes virus (KSHV). However, the role of PI3V-kinase in KSHVassociated primary effusion lymphoma (PEL) is not known. To assess this, we studied survival and apoptosis in PEL cell lines following inhibition of PI3V-kinase. Experimental Design: Constitutive activation of several...
