The effect of furosemide on gentamicin excretion and tissue accumulation was studied with clearance techniques in anesthetized rats, at two different infusion rates of saline or Ringer solution. Gentamicin ( approximately 20 mg/kg) was administered by constant intravenous infusion over a period of 3 h. With the low fluid infusion rate, furosemide (25 mg/kg intravenously) caused severe reduction...

In this talk we consider a Darcy flow problem coupled with a deposition function. Our model arises in the context of filtration, where a fluid carrying some particulate flows through some porous medium. As the particulate deposits, the porosity of the filter changes, modifying the flow conditions. In the talk we will motivate the model, discuss the existence and uniquess of our problem, provide...

A review on pleural space is certainly most welcome, for the simple reason that on opening a textbook of physiology the concepts concerning pleural fluid turnover date back to 1927 [1]. The same comment, in fact, applies in general to microvascular water and solute exchange. This appears particularly misleading, considering the major advances achieved in the field over the last 70 yrs. Around t...

BACKGROUND Hydrochloric acid aspiration increases pulmonary microvascular permeability. The authors tested the hypothesis that partial liquid ventilation has a beneficial effect on filtration coefficients in acute acid-induced lung injury. METHODS Isolated blood-perfused rabbit lungs were assigned randomly to one of four groups. Group 1 (n = 6) served as a control group without edema. In grou...

Production of urine is initiated by fluid and solute flux across the glomerular filtration barrier. Recent ultrastructural studies have shown that under extreme conditions of no filtration, or very high filtration, a restriction to flow is predicted in a space underneath the podocyte cell body or its processes, the subpodocyte space (SPS). The SPS covered up to two-thirds of the glomerular filt...

This study compared the fluid filtration, adaptation to the root canal walls, and the push-out bond strength of two resin-based sealers and three calcium silicate-based retrograde filling materials. Fifty maxillary canines were shaped using manual instruments and the apical portion was sectioned. Retrograde cavities of 3-mm depth were prepared. The specimens were divided into five groups (n = 1...

Direct flow (sometimes called “dead end”) filtration is applied when all the fluid to be filtered is driven, typically in industrial applications due to a supply pressure, in a direction perpendicular to a filtering surface; few applications are done by gravity feed. Contaminants are captured within the filtration media or build up on the surface, causing the differential pressure across the fi...

STATEMENT OF PROBLEM Sealing the perforation defect is an important factor to reduce inflammation in the area and to perform healing. Selecting the appropriate material to repair the defect is an important concern. Among the various available materials, MTA and CEM are used recently for achieving this purpose. In the current study we compare the sealing ability of these materials by evaluating ...

1. Physical and chemical parameters were measured in the Japanese oyster Crassostrea gigas to investigate whether the first step of urine formation in the lamellibranchs could be an ultrafiltration and to give a quantitative description. 2. The effective filtration pressure was not constant, but a function of time, oscillating between 317mmH2O and —3-8mmHzO. During the filtration, a separation ...

Convective fluid motion through artery walls aids in the transvascular transport of macromolecules. Although many measurements of convective filtration have been reported, they were all obtained under constant transmural pressure. However, arterial pressure in vivo is pulsatile. Therefore, experiments were designed to compare filtration under steady and pulsatile pressure conditions. Rabbit car...