Topology optimization of fluid dynamical systems is still in its infancy, with its first academic realizations dating back to as late as three years ago. In this paper, we present two approaches to fluid dynamic topology optimization that are based on potential flows and adjoint states, respectively. Special emphasis is paid to the computation of topological sensitivities with discrete adjoints...

Abstract Introduction Fluid optimization is an important feature in haemodynamic resuscitation. Despite recent advances, fluid management in clinical practice remains sometimes highly empirical. Well-defined endpoints of resuscitation, not only global but also focused on the microcirculatory level, as well as the correct timing for fluids administration, always according to any of the available...

delivery of exogenous materials such as nucleic acids, peptides, proteins, and drugs into cells is an important strategy in modern cellular and molecular biology. recently, the development of gene carriers for efficient gene transfer into cells has attracted a great attention. furthermore, lack of effective drug delivery is one of the major problems of cancer chemotherapy. many physical methods...

(1) Berkeley Sensor and Actuator Center – University of California at Berkeley – 497 Cory Hall – Berkeley, California, 94704 U.S.A. Tel +1 (510) 642 4876, Fax +1 (510) 643 6637, Email [email protected] (2) Berkeley Sensor and Actuator Center – University of California at Berkeley – 497 Cory Hall – Berkeley, California, 94704 U.S.A. Tel +1 (510) 642 9360, Fax +1 (510) 643 6637, Email liepman...

sulphide was determined spectrophotometrically at 628 nm and ph 6.7 based on its catalytic reduction of toluidine blue in the presence of se(iv) using a flow injection system. after optimization of the measuring conditions the calibration curve was found linear up to 25 mg/ml and the detection limit was 0.3 mg/ml (30 ml injections). the relative standard deviation for the determination of 10 mg...

For optimization of geological carbon sequestration (GCS) in saline aquifers, a genetic algorithm (GA) based optimizer has been developed and combined with the DOE multi-phase flow and heat transfer numerical simulation code TOUGH2 [1],[2]. Designated GA-TOUGH2, this combined solver/optimizer has been validated by performing optimization studies on a number of model problems and comparing the r...

If an air flow is injected into a liquid fluid, many ambulant air bubbles are formed inside the fluid. Air bubbles move inside the liquid fluid because of the buoyancy force, and the mobility of these air bubbles makes sizable commixture and turbulence inside the fluid. This mechanism was employed to enhance the heat transfer rate of a horizontal double pipe heat exchanger in this paper. Howeve...

This paper presents an efficient optimization procedure to find the optimal shapes of double curvature  arch  dams  considering  fluid–structure  interaction  subject  to  earthquake  loading. The optimization is carried out using a combination of the magnetic charged system search, big bang-big crunch algorithm and artificial neural network methods. Performing the finite element  analysis  dur...

The optimal design of the thrust vector control system solid rocket motors (SRMs) is discussed. injection a supersonic underexpanded gas jet into diverging part engine nozzle considered, and multiparameter optimization geometric shape parameters flow developed. turbulent viscous compressible in main simulated with Reynolds-averaged Navier–Stokes (RANS) equations shear stress transport (SST) tur...

   Drilling fluids are an essential component of the rotary drilling process used to drill for oil and gas on land and offshore environments. The injection of this nano particle into drilling fluid increases the viscosity levels fluids. In these experiments, the rheological properties of the fluid including apparent viscosity (AV), plastic viscosity (PV), yielding point (YP), mud c...