Pain upon negative pressure wound therapy (NPWT) dressing removal has been reported and is believed to be associated with the observation that granulation tissue grows into foam. Wound tissue damage upon removal of the foam may cause the reported pain. Calcitonin gene-related peptide (CGRP) and substance P are neuropeptides that cause inflammation and signal pain and are known to be released wh...

BACKGROUND Hemostatic dressings have become increasingly popular as the optimal initial treatment for severe hemorrhage. The purpose of this study was to compare the hemostatic properties of a novel highly porous silica and chitosan-based dressing (TraumaStat) to HemCon, and gauze dressing in a severe groin injury model in swine. METHODS Thirty swine were blindly randomized to receive TraumaS...

This study investigates the effects of five decontamination methods on the filter quality (qf) of three commercially available electret masks-N95, Gauze and Spunlace nonwoven masks. Newly developed evaluation methods, the overall filter quality (qf,o) and the qf ratio were applied to evaluate the effectiveness of decontamination methods for respirators. A scanning mobility particle sizer is uti...

Abstract Proteins are biocompatible, metabolizable, and susceptible to surface changes legend attachments for targeted distribution, therefore ideal materials nanoparticle-based drug delivery applications. The production, characterization, use of gelatin nanoparticles (GNPs) intracellular administration weakly cell-penetrating antibiotics (such as spectinomycin chloramphenicol) enhance their tr...

BACKGROUND Tracheostomy site infection can cause numerous problems. Absorbent foam dressing may be able to prevent proliferation of infectious microorganisms by absorbing the tracheostomy stoma exudate. This study aimed to compare the efficacy of absorbent foam with gauze dressing for prevention of tracheostomy site infection. MATERIALS AND METHODS In this double-blind randomized clinical tri...

OBJECTIVE To determine if a dry fibrin sealant dressing (DFSD) will provide superior hemostasis when compared with regular gauze in a ballistic injury animal model. DESIGN A nonsurvival randomized goat study. SETTING A federal biomedical research institute. SUBJECTS Eighteen anesthetized Angora goats. INTERVENTIONS Uncontrolled hemorrhage was induced by a complex ballistic extremity inj...

Cases of retained surgical guaze are rarely reported because of medico-legal and professional implications. Retained gauze for a period of more than 10 years is even rarer. A case of retained surgical gauze for 11 years, an accidental finding from a plain radiograph of a patient who had sustained proximal femoral fracture, is reported. A review of other reported cases is presented.

PURPOSE We perform a clinical retrospective study to determine whether a vaginal balloon-packing system provides a dosimetric reduction to organs at risk (OARs) versus traditional gauze packing for gynecological high-dose-rate brachytherapy (HDR-BT). We also test various balloon filling materials for optimizing imaging quality. MATERIAL AND METHODS Filling materials for balloon-packing were e...

Introduction: Gossypiboma is a serious but uncommon complication of surgical interventions. Most case reports and reviews refer to abdominal or thoracic surgery. Retained postoperative foreign bodies in limb or spine surgery are less commonly encountered. We present a case of gossypiboma in a paraplegic patient originating from pararectal surgery and detected 15 years after index surgery for in...

OBJECTIVE To assess the optimal method for covering smallpox vaccination sites to prevent transmission of vaccinia. DESIGN Randomized, nonblinded clinical trial. SETTING Tertiary care medical center. PARTICIPANTS Vaccinia-naive and vaccinia-experienced volunteers. INTERVENTIONS After vaccination, study participants were randomized to receive 1 of 3 types of bandage: gauze, occlusive wit...