1 Department of Forensic Medicine and Veterinary Toxicology, Faculty of Veterinary Medicine, South Valley University, 83523 Qena-Egypt 2 Department of Medical Laboratories, Collage of Applied Medical Sciences, Majmaah University-Kingdom of Saudi Arabia 3 Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Sıhyyie/Ankara-Türkiye 4 Division of Cerebral Circuitry, N...

Pharmacogenetic and Pharmacogenomics are the study of association between an individual's genotype their response to xenobiotics Pharmacokinetic pharmacodynamics variations can appear at level drug-metabolizing enzymes, drug transporters, targets or other biomarker genes. can, therefore, be relevant in forensic toxicology. This review presents aspects together with some examples from daily rout...

From the Department of Forensic Medicine, Kasturba Medical College, Mangalore, India Received: Nov. 11, 2014; Accepted: Jan. 13, 2015 Correspondence to: Dr. Tanuj Kanchan, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Mangalore, Manipal University, India. State Highway 65, Madhav Nagar, Manipal, India. Tel.: 91‐9448252394; Fax: 91‐824‐2428183; E‐mail: tanuj.kanchan@ ...

The toxicology community should be aware that pharmaceutical companies are developing deuterated analogues of therapeutic agents, purported to have improved margins of safety and reduced potential for drug interactions, according to a recent report (1). According to the article in Nature, companies are " snapping up intellectual property rights " on many of the modified drugs. Earlier this year...

Forensic toxicology is a highly specialized area of forensic science which requires expertise in analytical chemistry, pharmacology, biochemistry, and forensic investigation. The practicing forensic toxicologist is concerned not only with the isolation and identification of drugs and other pOlsons from tissues, but also with the interpretation of his findings for the medical examiner, coroner, ...

Background: The analysis of ethanol in bio-samples is an important method for determination of acute alcohol use/abuse both in clinical and forensic toxicology. In forensic cases, it is known that micro-organisms involved in the postmortem putrefaction process can produce alcohol and when the body has been traumatized. In clinical setting, post-ingestion time has a critical role for determinati...

There is no greater analytical challenge in forensic toxicology than the “general unknown,” the search for drugs or poisons that might have caused a death, impaired a driver or drugged the victim of sexual assault. Typically, the first step in such an analysis is one or more screening procedures, each designed to detect a number of analytes in a single analytical pass. All else being equal, the...

Gas chromatography in combination with mass spectrometry (GC-MS) plays an important role in the field of analytical toxicology. The identification of unknown compounds is very frequently undertaken with GC-MS and utilizing mass spectral libraries. Currently available libraries for analytical toxicology were compared for overlapping and uniqueness of their entries. Furthermore, the widely known ...