in order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. the commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. the release of therapeutic agents in vitro from medicated sp...

Systems undergoing ®rst-order phase transitions are accompanied by free energy barriers which separate the free energy minima characterizing the co-existing phases. These barriers grows with increasing system size. With conventional Monte Carlo simulation methods the characteristic time for crossing the barriers grows exponentially with system size and the system will necessarily get trapped in...

the main purpose of this study was to investigate the major barriers to application of good agricultural practices (gaps) technologies in sustainability of livestock by ranchers of meshkinshahr. a sample of 120 farmers was selected by using proportional random sampling method. data were collected by means of a questionnaire. validity of questionnaire was determined through agricultural jihad ex...

"Rapoport's rule," which has gained wide acceptance as a potential explanation for latitudinal and other diversity gradients, holds that mean latitudinal range of species decreases toward the equator. We analyzed latitudinal ranges of 2838 eastern Pacific marine molluscan species, a subset of which figured in the original formulation of Rapoport's rule, and failed to find the predicted trends. ...

This survey was intended to gauge the management of pain in palliative cancer patients by the doctors in Melaka Hospital. It also sought to identify possible barriers to adequate pain management among doctors and gauge their response to the adequacy of medical school teaching on cancer pain issues. A 39 item survey was used to cover the issues involved. Overall, the doctors displayed a lack of ...

We consider an extension of ordinary linear programming (LP) that adds weighted logarithmic barrier terms for some variables. The resulting problem generalizes both LP and the problem of finding the weighted analytic center of a polytope. We show that the problem has a dual of the same form and give complexity results for several different interior-point algorithms. We obtain an improved comple...

In this study new free-trade agreements are discussed, which are based on the breaking down of tariff and technical barriers and normally exclude most of the poorest countries in the world. Considering the current context of economic globalization and its health impacts, seven controversial points of these treaties and their possible implications for global public health are presented, mainly r...

Sparsity is a very powerful prior for the identification of signals from noisy indirect measurements. The recovery of the signal is usually performed by suitable linearly constrained optimizations with additional sparsity enforcing barriers. Depending on the specific formulation, one can produce a variety of different algorithms. In this Chapter the numerical realizations of such linear and non...

Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in design of programmed molecular systems. Current heuristics are not guaranteed to find the exact energy barrier, raising the question whether the energy barrier can be calculated efficiently. In this paper, we study the com...

Nanoengineered particles that can facilitate drug formulation and passively target tumors have reached the clinic in recent years. These early successes have driven a new wave of significant innovation in the generation of advanced particles. Recent developments in enabling technologies and chemistries have led to control over key particle properties, including surface functionality, size, shap...