Keep up with our latest articles, news and events. Plus, get special offers and more delivered to your inbox. Articles News Events Videos White Papers/Application Notes Featured Products Posters Issue Archives Home Bioprocessing Chromatography Excipients Drug Delivery Formulation Development Instrumentation Microbiology Spectroscopy Search American Pharmaceutical Review Welcome Guest Sign In Re...

The design of a melt synthesis of the first air-stable formulation of the metastable form III of paracetamol is derived from thermo-spectroscopic and thermo-diffraction experiments. Melt crystallisation in the presence of β-1,4-saccharides produces form III selectively and the excipients appear to act as stabilising 'active' templates of the metastable polymorph.

2 List of all formulations aranged.In the present study, the design of an oral effervescent tablet of diclofenac potassium was carried out. Six different formulations were prepared using different.The objective of the present study was to formulate aspirin tablets by direct. Method using fewer excipients and to compare this formulation with the other. Study was to formulate Effervescent tablet ...

Microspheres can be tailored to provide targeted and/or sustained release in different parts of the body, including those of eye, nasal cavity, urinary, colon and gastrointestinal tract, thus offering the possibilities of localized as well as systemic controlled release of drugs. Prolonged release of drugs and a reduction in frequency of drug administration can highly improve the patient compli...

The aim was to enhance the dissolution of lornoxicam (LOR) and to produce mini-tablets with an optimised system to provide a rapid-release multi-particulate formulation. LOR systems were prepared through co-evaporation with either polyethylene glycol 6000 or Pluronic(®) F-68 (PLU) and adsorption onto Neusilin(®) US2 alone or co-adsorption in the presence of different amounts of polysorbate 80. ...

The present study was an attempt to investigate the feasibility of the matrix based sustained release unit dosage formulation of cefixime trihydrate. Matrix tablets were prepared by using xanthan gum along with the other polymer combinations (Guar gum, sodium alginate and hydroxypropylmethyl cellulose). Effect of different formulation variables like polymer concentration, ratio of polymer combi...

candesartan cilexetil (cc) is a newer class of angiotensin ii receptor antagonist used for the treatment of hypertension. the solubility of the cc is very poor and its oral bioavailability is only 15%. the controlled-release polar lipid microparticles of cc (formulations f1, f2, f3 and f4) were prepared using variable erodible lipophilic excipients like hydrogenated castor oil, stearic acid, ce...