Background: The interaction between antiepileptic drugs and brain electrical stimulation is a potential therapy to control of seizures in patient with pharmacoresistance to drugs. So, the aim of present study was designed to determine the effect of a sub effective dose of sodium valproate combined with low-frequency electrical stimulation during kindling. Material and Methods: One tripolar ele...

This review discusses the advancements that are needed to enhance the effects of electrical stimulation for restoring or assisting movement in humans with an injury/disease of the central nervous system. A complex model of the effects of electrical stimulation of peripheral systems is presented. The model indicates that both the motor and sensory systems are activated by electrical stimulation....

Lower urinary tract disorders and colorectal diseases like faecal incontinence often are caused by neurological disorders. One solution is functional restoration via the pathways of the nervous system by electrical stimulation of the involved nervous tracts. New basic and clinical research suggest that peripheral and more superficial techniques can successfully applied to correct functional uro...

A novel, self-contained controller for functional electrical stimulation systems has been designed. The development was motivated by the need to have a general purpose, easy to use controller capable of stimulating many muscle groups, thus restoring complex motor functions (e.g. standing, walking, reaching, and grasping). The designed controller can regulate the frequency, pulse duration, and c...

The application of engineering control theory to biological systems is a challenge. Often, in initial engineering models or designs of systems to exert control over a certain aspect or part of a biological system, other control loops may be in operation within the biological system that are not accounted for. When the operation of such unconsidered hidden loops reveals themselves, this presents...

For over 40 years, research labs have been developing gait assist systems that use electrical stimulation of muscle to restore function to limbs paralyzed as a result of spinal cord injury. The concept of functional electrical stimulation (FES) is simple, but realization is challenging. While there are some similarities between FES-aided gait and a bipedal robot walking machine, there are also ...

Functional electrical stimulation (FES) refers to electrical stimulation of muscles in order to improve the impaired motor function. This is achieved by activating skeletal muscles with constant frequency trains of stimulations. This method has been found useful in various neurological disorders like hemiplegia, foot drop and paraplegia including spinal cord injuries. The first half of this rev...