background and objective: chronic rhinosinusitis (crs) is one of the most common chronic diseases. in the past decades, there has been an increase in fungal infections of sinuses and fungal rhinosinusitis (frs) has been diagnosed more frequently. knowing the fungal flora and its prevalence in crs patients will allow a better understanding of this disease, permitting a correct diagnosis, treatme...

When it comes to biodefense and preparedness, the fungal kingdom is often a late afterthought. For example, among the original agents in the select agents list that were pathogenic for humans, only one fungus, Coccidioides immitis, was included, but the same organism was initially left out of the NIH priority agents list. This made laboratories working on this important pathogenic fungus subjec...

Invasive fungal diseases are associated with a high morbidity and mortality, particularly in the context of immunosuppression. Diagnosis of invasive fungal diseases is usually complicated by factors such as poor clinical suspicion and unspecific clinical findings. Access to modern diagnostic tools is frequently limited in developing countries. Here, we describe five real-life clinical cases fro...

OBJECTIVE OF THE STUDY An estimation of burden of serious fungal diseases in France is essential data to inform public health priorities on the importance of resources and research needed on these infections. In France, precise data are available for invasive fungal diseases but estimates for several other diseases such as chronic and immunoallergic diseases are by contrast less known. MATERI...