Akira Saito1*, Emiko Saito2, Yasuo Ueda1, Yoshihiro Shibukawa3, Yoshiyuki Honma4, Tomomi Takahashi4, Mariko Kimura5, Yoshinori Kuboki6 and Hiroshi kato7 1Department of Oral Rehabilitation, Division of Oral Functional Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan. 2Departments of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido Univers...

The objectives of this study were to measure the Furcation Entrance Dimensions of first and second permanent molars in Malaysian samples and to compare the Furcation Entrance Dimensions with the blade widths of periodontal Gracey’s curette used for root surface instrumentation. A total of 199 extracted permanent teeth were measured, which comprised of 51 mandibular first molars, 51 mandibular s...

OBJECTIVES Stem cell-based therapy promises to regenerate lost tissue. Embryonic stem (ES) cells are pluripotent and may provide a virtually unlimited source for transplantation. We investigated whether ES cell transplantation improved the regeneration of furcation defects in a porcine model. MATERIAL AND METHODS Experimental periodontitis was induced in the buccal furcations of the bilateral...

One of the most important indications for guided tissue regeneration (GTR) treatment is class II furcation lesion. However, periodontal regeneration of this type of defect, although possible, is not considered totally predictable, especially in terms of complete bone fill. Many factors may account for variability in the response to regenerative therapy in class II furcation. The purpose of this...

The purpose of this study was to evaluate the efficacy of porous hydroxyapatite (HAP) as an implant material into human periodontal defects. Thirty three patients affected by marginal periodontitis were studied. Following initial therapy, 44 periodontal osseous defects received grafts of HAP granules and blocks during flap surgery. Radiographic and various clinical examinations were performed b...

BACKGROUND AND OBJECTIVE Periodontal disease is a common infectious disease, found worldwide, causing the destruction of the periodontium. The periodontium is a complex structure composed of both soft and hard tissues, thus an agent applied to regenerate the periodontium must be able to stimulate periodontal ligament, cementum and alveolar bone regeneration. Recent studies demonstrated that ace...