The mitotic spindle determines the cleavage furrow site during metazoan cell division, but whether other mechanisms exist remains unknown. Here we identify a spindle-independent mechanism for cleavage furrow positioning in Drosophila neuroblasts. We show that early and late furrow proteins (Pavarotti, Anillin, and Myosin) are localized to the neuroblast basal cortex at anaphase onset by a Pins ...

c-Myc (Myc) oncoprotein induction of genomic instability (GI) contributes to its initial transforming function and subsequent tumor cell evolution. We describe here a pathway by which Myc, via its target protein glycoprotein Ibalpha (GpIb alpha), mediates GI. Proteomic profiling revealed that the serine/threonine kinase Aurora B is down-regulated by GpIb alpha in p53-deficient primary human fib...

Different furrow openers are required to be evaluated for their suitability to manage rice straw for direct planting of wheat in paddy fields. This study was carried out to assess the straw-cutting ability and draft requirements of four different disc-type furrow openers (notched, toothed, smooth-edge single disc, and double disc) in no-till paddy fields. The openers were attached to an in-fiel...

The article provides a biomechanical analysis of ventral furrow formation in the Drosophila melanogaster embryo. Ventral furrow formation is the first large-scale morphogenetic movement in the fly embryo. It involves deformation of a uniform cellular monolayer formed following cellularisation, and has therefore long been used as a simple system in which to explore the role of mechanics in force...

Cytokinesis in early zebrafish embryos involves coordinated changes in the f-actin- and microtubule-based cytoskeleton, and the recruitment of adhesion junction components to the furrow. We show that exposure to inhibitors of non-muscle myosin II function does not affect furrow ingression during the early cleavage cycles but interferes with the recruitment of pericleavage f-actin and cortical b...

During cytokinesis, cleavage furrow invagination requires an actomyosin-based contractile ring and addition of new membrane. Little is known about how this actin and membrane traffic to the cleavage furrow. We address this through live analysis of fluorescently tagged vesicles in postcellularized Drosophila melanogaster embryos. We find that during cytokinesis, F-actin and membrane are targeted...

up to now, interactions between method and amount of nitrogen fertilizers application on plant density and variety of wheat under sprinkler irrigation systems have not been studied. thus, this research was conducted during two years in esfehan region with split factorial design. the treatments of this experiment were: three fertilizers application methods (conventional manual application at the...

A trickle irrigation experiment on sugarcane was established in October 1985 on the SASA Experiment Station farm at Shakaskraal. The objectives were to establish suitable operating procedures, to measure cane yield potential, and to study the effects of factors such as fertigation and crop row spacingon yieldsoftrickle irrigated sugarcane. The results ofthe plant and first ratoon crops of this ...

Cytokinesis by contraction of the base of the cleavage furrow and the dependence of the position of the future furrow on the arrangement of cytoplasm under it have been demonstrated at relatively earlier stages of cleavage in amphibian eggs. The following experiments and observations on dividing eggs of the newt Cynops pyrrhogaster indicated the presence of the contracting force at the base of ...