The B domain of staphylococcal protein A (BdpA) is a small helical protein that has been studied intensively in kinetics experiments and detailed computer simulations that include explicit water. The simulations indicate that BdpA needs to reorganize in crossing the transition barrier to facilitate folding its C-terminal helix (H3) onto the nucleus formed from helices H1 and H2. This process su...

We find limiting distributions of the nonparametric maximum likelihood estimator (MLE) of a log-concave density, i.e. a density of the form f(0) = exp varphi(0) where varphi(0) is a concave function on R. Existence, form, characterizations and uniform rates of convergence of the MLE are given by Rufibach (2006) and Dümbgen and Rufibach (2007). The characterization of the log-concave MLE in term...

The fluidity of liquid metals, like that of simple nonmetallic liquids, is a linear function of the ratio of unoccupied volume to intrinsic volume over long ranges as expressed by the equation varphi = B[(V/V(0)) - 1]. Values of V(0) obtained by extrapolating to varphi = 0 agree well with molal volumes of compact crystals at 20 degrees C calculated from densities.Values of the ratio varphi/[(V/...

Recent efforts to broaden understanding of the molecular mechanisms of membrane receptors in signal transduction make use of rate-equilibrium free-energy relationships (REFERs), previously applied to chemical reactions, enzyme kinetics, and protein folding. For oligomeric membrane receptors, we distinguish between a), the Leffler parameter alpha(L), to characterize the global transition state f...

‎Let $\Omega_X$ be a bounded‎, ‎circular and strictly convex domain in a complex Banach space $X$‎, ‎and $\mathcal{H}(\Omega_X)$ be the space of all holomorphic functions from $\Omega_X$ to $\mathbb{C}$‎. ‎The growth space $\mathcal{A}^\nu(\Omega_X)$ consists of all $f\in\mathcal{H}(\Omega_X)$‎ ‎such that $$|f(x)|\leqslant C \nu(r_{\Omega_X}(x)),\quad x\in \Omega_X,$$‎ ‎for some constant $C>0$‎...

A signed graph is a simple with two types of edges: positive and negative. homomorphism from G to another H mapping \(\varphi : V(G) \rightarrow V(H)\) that preserves vertex adjacencies balance closed walks (the the parity number negative edges). The chromatic \(\chi _s(G)\) order smallest such there H.

We show that a qubit can be used to substitute for a classical analog system requiring an arbitrarily large number of classical bits to represent digitally. Let a physical system S interact locally with a classical field varphi(x) as S travels directly from point A to point B. Our task is to use S to answer a simple yes/no question about varphi(x). If S is a qubit, the task can be done perfectl...

best approximation results provide an approximate solution to the fixed point equation $tx=x$, when the non-self mapping $t$ has no fixed point. in particular, a well-known best approximation theorem, due to fan cite{5}, asserts that if $k$ is a nonempty compact convex subset of a hausdorff locally convex topological vector space $e$ and $t:krightarrow e$ is a continuous mapping, then there exi...

Abstract Let G be a finite group with exactly k elements of largest possible order m . q ( ) the product $$\gcd (m,4)$$ gcd ( m , 4 ) and odd prime divisors We show that $$|G|\le q(m)k^2/\varphi (m)$$ <...