Melissa officinalis L. (Labiatae) traditionally used in treating neurological disorders has also been identified as a memory-enhancing herb. The extract of M. officinalis has a cholinergic property. The role of basal forebrain cholinergic neurons, the neurons that are destroyed in Alzheimer's disease (AD), in learning and memory, is also well known. The aim of this study is to investigate the r...

The chemical composition and bioactive properties of two plants (Calendula officinalis L. and Mentha cervina L.) were studied. Their nutritional value revealed a high content of carbohydrates and low fat levels, and very similar energy values. However, they presented different profiles in phenolic compounds and fatty acids; C. officinalis presented mainly glycosylated flavonols and saturated fa...

The antioxidant activity and total phenolic content of some spices (M. piperita L., R. coriaria L., T. spicata, S. officinalis, R. officinalis L., C. ovata L., O. vulgare L., L. nobilis L. and C. annum L.) were determined. The higher TEAC values (mmol TE/g extract) were obtained for sage (1.783) and rosemary (1.241). The IC value (mg/ml) ranged between 0.103-4.082 for mint and capers, respectiv...

The aim of the present study was to evaluate hypnotic effect of Coriandrum sativum, Ziziphus jujuba, Lavandula angustifolia and Melissa officinalis hydroalcoholic extracts in mice to select the most effective ones for a combination formula. Three doses of the extracts (250, 500 and 1000 mg/kg of C. sativum and Z. jujuba and 200, 400 and 800 mg/kg of L. angustifolia and M. officinalis) were oral...

The aqueous extracts of sweet basil (Ocimum basilicum L.), tarragon (Artemisia dracunculus L.), fennel (Foeniculum vulgare Miller), olive (Olea europaea L.), sage (Salvia officinalis L.), thyme (Thymus vulgaris L.), wild thyme (T. serpyllum L.), tea (Camellia sinensis (L.) Kuntze), and verbena (Verbena officinalis L.) were investigated for polyphenol, tannins, antocyanins and flavonoids. Among ...

In the present study, we report the finding of high concentrations of D-Asp (D-aspartate) in the retina of the cephalopods Sepia officinalis, Loligo vulgaris and Octopus vulgaris. D-Asp increases in concentration in the retina and optic lobes as the animal develops. In neonatal S. officinalis, the concentration of D-Asp in the retina is 1.8+/-0.2 micromol/g of tissue, and in the optic lobes it ...

Radio protective effects of metformin and its ability to alter the spontaneous induced genotoxic cytotoxic levels on human peripheral blood lymphocytes were investigated in this study. Metformin, a hypoglycemic oral drug, is biguanide derived from Galega officinalis that widely utilized controlling type 2 diabetes mellitus. Whole samples 10 healthy donors (5 males 5 females) exposed two doses g...