نتایج جستجو برای: gallium compounds
تعداد نتایج: 242016 فیلتر نتایج به سال:
On the basis of enhanced tumor accumulation and bone affinity, gallium compounds are under development as anticancer and antimetastatic agents. In this study, we analyzed molecular targets of one of the lead anticancer gallium complexes [KP46, Tris(8-quinolinolato)gallium(III)] focusing on colon and lung cancer. Within a few hours, KP46 treatment at low micromolar concentrations induced cell bo...
The reactivity of a series of Ga(I), Ga(II) and Ga(III) heterocyclic compounds towards a number of Group 15 substrates has been investigated with a view to prepare examples of gallium-terminal pnictinidene complexes. Although no examples of such complexes were isolated, a number of novel complexes have been prepared. The reactions of the gallium(I) N-heterocyclic carbene analogue, [K(tmeda)][:G...
The reactions of two diazabutadiene ligands, Ar-DAB [(ArN CH)2, Ar = 2,6-Pr2C6H3] and Bu-DAB [(BuN CH)2] with either GaI or an AlI3/Al mixture have afforded the paramagnetic compounds, [{IGa (Bu-DAB)}2], [I2Ga (Bu-DAB)] and [I2Al (Ar-DAB)] which have been characterised by X-ray crystallography and EPR spectroscopy. In addition, the diamagnetic, ionic complex, [I2Al (Ar-DAB)]I, has been prepared...
1- in a search directed to the reaction of compound)23(the cycloaddition reaction of 1,3- diphenylisobenzofurane)14(with p-benzoquinone)19(,followed by addition of cyclopentadiene was carried out.the specific spacial stracture of its ir,nmr,mass spectra. 2- in another attempt the kinetic stability and behavior of compounds)20(and)23(was studied.the main subject of this study was the highly reve...
The opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa) causes infections that are difficult to treat, which is due the bacterial natural resistance antibiotics. bacterium also able to...
چکیده ندارد.
A mouse model of cystitis caused by uropathogenic Escherichia coli was used to study the distribution of gallium in bladder tissue following oral administration of gallium maltolate during urinary tract infection. The median concentration of gallium in homogenized bladder tissue from infected mice was 1.93 μg/g after daily administration of gallium maltolate for 5 days. Synchrotron X-ray fluore...
that the gallium activity was located near the stomach. After another glass of water was taken, the stomach was imaged again, using the upper three gallium peaks and thus excluding the Tc99m energy. This showed that the gallium activity was no longer present in the stomach (Fig. I). Gallium and Tc-99m were seen on the oscilloscope to enter the small bowel. An image taken 30 min later did not sh...
The extractabilities of aluminium(III), gallium(III), and indium(III) from hydrochloric acid solutions were investigated using a mixture of two protic ionic liquids, trioctylammonium bis(trifluoromethanesulfonyl)amide ([TOAH][NTf(2)]) and trioctylammonium nitrate ([TOAH][NO(3)]). At a HCl concentration of 4 mol L(-1) or more, gallium(III) was nearly quantitatively extracted and the extractabil...
Gallium is a group IIIa metal that has efficacy in the therapy of malignant disorders such as lymphoma and urothelial tract tumors. Preclinical studies also indicate a role for gallium in autoimmune disorders, suggesting that gallium is able to modulate T-cell immune reactivity. The purpose of this study was to examine the in vitro and in vivo immunomodulatory action of gallium on T-cell functi...
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