We investigated the effect of NC-1300-O-3 on gastric mucus secretion and prostaglandin release into the gastric lumen in rats. NC-1300-O-3 following single or repeated administration for up to 4 weeks significantly increased the hexose content in the gastric lumen at 10 to 100 mg/kg, p.o. Omeprazole and cimetidine at doses that strongly inhibited gastric acid secretion had no effect on the hexo...

AIM Some amino acids been known to influence gastric emptying. Thus we have evaluated the effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying. MATERIALS AND METHODS Gastric emptying was evaluated in rats after feeding with Racol (nutrient formulae) containing [1-(13)C] acetic acid. Using a breath test, the content of (13)CO2 in th...

hydrogen sulfide (h2s) has been shown to protect the gastric mucosa through several protective mechanisms but till now its effect on mrna expression of sodium bicarbonate cotransporter 1 (nbc1), trefoil factor1 (tff1) and trefoil factor2 (tff2) was not investigated. this study was aimed to evaluate the effect of h2s on mrna expression of nbc1, tff1 and tff2 in rat gastric mucosa in response to ...

Subcutaneous administration of mepirizole (60 and 200 mg/kg) and cysteamine (100 and 300 mg/kg) to fasted rats consistently induced localized villous damage to the proximal duodenum after 6 to 8 hr. The severity of the damage in animals treated with the low doses remained unchanged at 12 hr. With the high doses, however, well-defined deep ulcers were evident by that time, the incidence being hi...

A fatal case involving flunitrazepam with ethanol ingestion is presented. Quantitative toxicological analysis revealed that the concentrations of 7-aminoflunitrazepam (a metabolite of flunitrazepam) and ethanol in a femoral blood sample were 0.175 μg/mL and 0.67 mg/mL, respectively. High concentration of flunitrazepam (24.3 μg/mL) was detected from the stomach contents, and 10.9 mg of flunitraz...

Studies have shown that reactive oxygen metabolites and lipid peroxidation play important roles in ischemia-reperfusion injury in many organs such as heart, brain and stomach. The aim of this study is to evaluate the antioxidant effect of L-carnitine on gastric mucosal barrier, lipid peroxidation and the activities of antioxidant enzymes in rat gastric mucosa subjected to ischemia-reperfusion i...

BACKGROUND Pulmonary aspiration of gastric contents leading to acid aspiration syndrome (AAS) is a well recognized risk factor during general anaesthesia (GA) for Caesarean section (CS). The cross sectional observational study was conducted during July 2008 to October 2008 at Department of Anaesthesiology and Intensive Care, Liaquat University of Medical & Health Sciences Jamshoro, Sindh, Pakis...

The conventional method used to study gastric secretion and activity involves the withdrawal and examination of specimens of gastric juice. Such a procedure subjects the average patient to considerable physical and emotional stresses. Further, the repeated collection of samples of gastric juice from a great number of individuals over a prolonged period of time presents many practical difficulti...

The presence of nematode or round worms in the flesh of marine fish has long been known and is perceived to be both an aesthetic and human health problem. The most abundant group are members of the genus Anisakis and within fish they are small, colourless worms which are found, often lightly coiled within the flesh or the viscera. Within the flesh they are often difficult to see with the naked ...

Avian carcasses can provide important information on the trophic ecology of birds. Usually, the number of carcasses available for examination is limited and therefore it is important to gain as much dietary information per specimen as possible. In piscivorous birds and raptors, the stomach has been the primary source of dietary information, whereas the gut (intestine) has so far been neglected ...