Background/Aims After exclusion of structural diseases, chronic constipation may be associated with normal or slow transit or rectal evacuation disorders. We evaluated: (1) clinical features and anorectal function, (2) difference of regional colonic transit according to the presence or absence of evacuation disorders, and (3) association of colonic transit with gender in patients with objective...

Dental erosion due to intrinsic factors is caused by gastric acid reaching the oral cavity and the teeth as a result of wmiting or gastroesophageal reflux. Since clinical manifestation of dental erosion does not occur until gastric acid has acted 011 the dental hard tissues regularly over a period of several years. dental erosion caused by intrinsic factors has been observed only in those disea...

background : gastric cancer as the fourth most frequent malignancy worldwide was known to have the highest rate among cancer-related disorders in ardabil province. the product of tp53 gene regulated  the cell cycle process and acts as a tumor suppressor factor. the polymorphism p53 arg72pro (rs1042522) has been reported to be associated with many type of cancers.  the purpose of the present stu...

Functional dyspepsia is a highly prevalent and heterogeneous disorder. Functional dyspepsia involves many pathogenic factors, such as gastric motility disorders, visceral hypersensitivity, psychological factors, Helicobacter pylori infection, and excessive gastric acid secretion. The present article provides an overview of pathogenetic factors and pathophysiologic mechanisms.

Gastric mucosal cells, particularly parietal and chief cells, are usually affected by exogenous, and endogenous stimuli-induced gastritis. The integrity of these cells and their alterations are involved in the pathogenesis of numerous gastric disorders. Omeprazole, a gastric acid secretion blocker, is commonly used for gastrointestinal diseases due to its antioxidative stress and anti-inflammat...

Many gastrointestinal complaints and motility disorders are described in patients suffering from different eating disorders. These have a negative impact on refeeding. This report evaluated—on admission—gastric emptying of a standardized solid meal with C octanoic acid breath test in anorexic adolescents. The results were compared with age and gender matched controls. Gastric emptying data were...

BACKGROUND Participatory gastric headache is a type of headache described in Iranian traditional medicine. It is defined as a headache not originated from the head and neck disorders; rather the pain in the head is caused by gastric dysfunction and its disorders. Treatment of this type of headache is completely reliant on the treatment of the gastric complaint. Reviewing Iranian traditional med...

Previous studies showed that symptoms of oesophageal motor disorders can be misinterpreted as indicating anorexia nervosa and that in primary anorexia nervosa gastric motility is frequently impaired. We investigated in 32 women with bulimia nervosa whether symptoms of oesophageal motor disorders could be obscured by or be mistaken as forming part of bulimic behaviour, and whether impaired gastr...

OBJECTIVES The stomach is a sensitive digestive organ that is susceptible to exogenous pathogens from the diet. In response to such pathogens, the stomach induces oxidative stress, which might be related to the development of both gastric organic disorders such as gastritis, gastric ulcers, and gastric cancer, and functional disorders such as functional dyspepsia. This study was accomplished to...

The maladies of gastric secretion, including peptic ulcer disease, gastritis, and esophageal reflux, represent common and pervasive disorders throughout our population. Investigations during the past two decades have led to remarkable and profound changes in the treatment of acid-peptic disorders. Medical treatments have evolved from gastric resection through the evolution of "physiological" an...