BSC1, which was originally identified by its sequence similarity to voltage-gated Na(+) channels, encodes a functional voltage-gated cation channel whose properties differ significantly from Na(+) channels. BSC1 has slower kinetics of activation and inactivation than Na(+) channels, it is more selective for Ba(2+) than for Na(+), it is blocked by Cd(2+), and Na(+) currents through BSC1 are bloc...

We evaluated exposed-radiation doses on dual-source cardiac computed tomography (CT) examinations with prospective electrocardiogram (ECG)-gated fast dual spiral scans. After placing dosimeters at locations corresponding to each of the thoracic organs, prospective ECG-gated fast dual spirals and retrospective ECG-gated dual spiral scans were performed to measure the absorbed dose of each organ....

We report the effect of remote surface optical (RSO) phonon scattering on carrier mobility in monolayer graphene gated by ferroelectric oxide. fabricate transistors back-gated epitaxial (001) Ba 0.6 Sr 0.4 TiO 3 films, with field up to 23 000 cm 2 V −1 s achieved. Switching polarization induces nonvolatile modulation resistance and quantum Hall at low temperatures. Ellipsometry spectroscopy stu...

Electrolyte-gated transistors have been proposed as promising candidates for neuromorphic applications. Synaptic plasticity behaviors and most recently synaptic metaplasticity or of mimicked on electrolyte-gated transistors. In this work, indium-gallium-zinc-oxide thin-film gated with sputtered SiO2 electrolytes are fabricated. Both spiking-width-dependent spiking-height-dependent successfully ...

AIM Respiratory motion affects cardiac PET-computed tomography (CT) imaging by reducing attenuation correction (AC) accuracy and by introducing blur. The aim of this study was to compare three approaches for reducing motion-induced AC errors and evaluate the inclusion of respiratory motion correction. MATERIALS AND METHODS AC with a helical CT was compared with averaged cine and gated cine CT...

Intensity difference limens (DLs) were measured in users of the Nucleus 22 and Clarion v1.2 cochlear implants and in normal-hearing listeners to better understand mechanisms of intensity discrimination in electric and acoustic hearing and to evaluate the possible role of neural adaptation. Intensity DLs were measured for three modes of presentation: gated (intensity increments gated synchronous...

Eslicarbazepine acetate is an advanced antiseizure medication that improvement upon carbamazepine and oxcarbazepine. This novel regulates voltage-gated sodium channels provides fewer adverse effects better tolerability. Herein, we present the characteristics, pharmacokinetics, drug interactions of eslicarbazepine based on research has been conducted to date. Key words: acetate; Pharmacokinetics...

OBJECTIVE Our goal was to determine the impact of ECG gating and different postprocessing techniques on 3D imaging of the bronchial tree. SUBJECTS AND METHODS. Retrospective ECG-gated MDCT and non-ECG-gated MDCT of the chest were performed in 25 patients. ECG-gated MDCT data were reconstructed mid diastole using a fixed interval of -400 msec in 25 patients and then additionally at -200, -300, a...

Voltage-gated ion channels play a fundamental role in the generation and propagation of the cardiac action potential by acting synergistically to produce an ionic current across cellular membranes. Abnormalities of heart ion channel activities that lead to loss or gain of function (channelopathies) are often associated with disruption of the coordinated propagation of electrical activity of the...

Quantitative four-dimensional (4D) image reconstruction methods with respiratory and cardiac motion compensation are an active area of research in ECT imaging, including SPECT and PET. They are the extensions of three-dimensional (3D) statistical image reconstruction methods with iterative algorithms that incorporate accurate models of the imaging process and provide significant improvement in ...