Does research on gender-based violence (GBV) pose greater than minimal risk to researchers and participants? This question needs to be understood particularly in light of hesitancy by Institutional Review Boards to approve research on GBV. The safety and risks of doing GBV studies and the implications for the ethical review process have not been a focus of much research. This qualitative study ...

In order to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection in dialysis patients and kidney transplant recipients in Central Brazil and also to analyze the virus genotypes distribution, a total of 123 patients including 98 on hemodialysis, 13 on continuous ambulatory peritoneal dialysis treatment, and 12 who received kidney transplantation were interviewed in ...

INTRODUCTION Persistent infection with GBV-C (GB Virus C), a non-pathogenic virus related to hepatitis C virus (HCV), prolongs survival in HIV infection. Two GBV-C proteins, NS5A and E2, have been shown previously to inhibit HIV replication in vitro. We investigated whether the GBV-C NS3 serine protease affects HIV replication. RESULTS GBV-C NS3 protease expressed in a human CD4+ T lymphocyte...

Some retrospective studies suggest an association between infection with GB virus-C (GBV-C) and non-Hodgkin lymphoma (NHL). We evaluated this association prospectively in a nested case-control study within the U.S. Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Cases (N = 658) and controls (N = 1,316) were individually matched by age, sex, race/ethnicity, timing of study ...

BACKGROUND Gender-based violence (GBV) has profound adverse consequences on women's physical, mental, and reproductive health. Although Vietnam has high rates of induced abortion and GBV, literature examining this relationship is lacking. OBJECTIVE This study examines the association of GBV with induced abortion among married or partnered women of reproductive age in Thai Nguyen province, Vie...

To the Editor: In the editorial Responding to Gender-based Violence in Disasters: Grappling With Research Methods to Clear the Way for Planning, Rosborough et al discuss challenges to measuring and reporting on gender-based violence (GBV) in disasteraffected populations.1 The authors also comment on our research contribution, which documented an increase in GBV among female internally displaced...

BACKGROUND The effect that GB virus C (GBV-C) coinfection has on human immunodeficiency virus type 1 (HIV-1) disease progression is controversial and therefore was studied in 326 homosexual men from the prospective Amsterdam Cohort Studies who had an accurately estimated date of HIV-1 seroconversion and were followed up for a median period of 8 years. METHODS A first plasma sample, obtained s...

BACKGROUND Previous studies in patients with hepatitis C virus (HCV)/HIV coinfection have shown that the presence of GBV-C is associated with significantly less compensated and decompensated cirrhosis, and an improvement in cirrhosis-free survival. OBJECTIVES This study aimed to describe the effect of GBV-C in patients with chronic hepatitis C and HIV coinfection. PATIENTS AND METHODS We re...

1 1. What we know about GB virus type C (Hepatitis G virus) 1 1.1. Molecular structure 1 1.2. History and distribution 1 1.3. Routes of transmission 2 1.4. Prevalence of GBV-C infection 2 1.4.1. Healthy blood donors 2 1.4.2. High risk populations 3 1.5. GBV-C detection methods 3 1.6. Natural history of GBV-C infection in humans 4 1.6.1. GBV-C and HIV co-infection 4 1.6.2. Biological mechanism o...

A molecular epidemiological study was performed to investigate the prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among various populations in Surabaya, Indonesia. The prevalence of GBV-C/HGV RNA, determined by reverse transcription-PCR for a portion of the NS3 region of the viral genome, was 2.7% (4 of 150) among randomly collected blood donor sera, which were all negative fo...