PURPOSE To evaluate changes in retinal nerve fiber layer (RNFL) thickness after laser in situ keratomileusis (LASIK) using a scanning laser polarimeter with fixed corneal compensation (GDx) and the retinal thickness analyzer (RTA). METHODS Thirty-eight eyes of 19 healthy subjects (10 female and 9 male; mean age 37.0-/+8.8 years) underwent GDx and RTA measurements before and after LASIK. All s...

Previous studies suggested that adults respond differently than pubertal male rats to cold stress. To test the role of androgens in this difference, we adrenalectomized and replaced with corticosterone either 60- or 40-day-old male rats, then sham gonadectomized (Intact), gonadectomized (GDX), or GDX and replaced with testosterone (T; GDX+T) or dihydrotestosterone (DHT). One-half remained at ro...

PURPOSE To evaluate the sensitivity and specificity for discriminating between early to moderate glaucomatous and normal eyes using summary data reports from the Heidelberg Retina Tomograph (HRT), the GDx Nerve Fiber Analyzer (GDx), and the Optical Coherence Tomograph (OCT). DESIGN Comparative cross-sectional study PARTICIPANTS One eye each of 50 normal subjects and 39 glaucoma patients wit...

The incidence of cardiovascular disease, including inflammatory heart diseases like myocarditis, is increased in men. Similarly, male BALB/c mice infected with coxsackievirus B3 (CVB3) develop more severe acute inflammation in the heart compared to females. To better understand the effect of male sex hormones on cardiac inflammation, we gonadectomized (Gdx) male BALB/c mice and examined acute C...

Purpose: To quantify the intraobserver reproducibility of retinal nerve fiber layer (RNFL) measurements using scanning laser polarimetry with variable corneal compensation in glaucoma suspect patients. Methods: Twenty-six eyes of 26 glaucoma suspect patients were included. Complete ophthalmologic examination and standard automated perimetry were performed for all of them. RNFL measurements were...

PURPOSE To evaluate quantitatively the intraobserver reproducibility of measurements of the retinal nerve fiber layer (RNFL) in healthy subjects and an ocular hypertensive population using two nerve fiber analyzers. METHODS Sixty eyes of normal (n=30) and ocular hypertensive subjects (n=30) were consecutively recruited for this study and underwent a complete ophthalmologic examination and ach...

AIMS To investigate the usefulness of the scanning laser polarimeter (GDx; GDx Nerve Fiber Analyzer) for glaucoma detection in the Japanese population, and to investigate the difference in the thickness of retinal nerve fibre layer (RNFL) between normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). METHODS 69 eyes of 69 normal subjects and 115 eyes of 115 chronic open angle g...

We report on results from experiments where human traders interact with software-agent traders in a real-time asynchronous continuous double auction (CDA) experimental economics system. Our experiments are inspired by the seminal work reported by IBM at IJCAI 2001 [Das et al., 2001], where it was demonstrated that softwareagent traders could consistently outperform human traders in real-time CD...

PURPOSE To determine whether the nerve fiber analyzer GDx with the new variable corneal compensation (VCC) device allows measurements of retinal nerve fiber layer parameters independent from birefringence changes of the cornea after photorefractive keratectomy (PRK). METHODS Retinal nerve fiber layers of 32 eyes in 32 myopic patients undergoing PRK were analyzed using the GDx-VCC. Photorefrac...

BACKGROUND AND OBJECTIVE The feasibility and reproducibility of scanning laser polarimetry performed through dilated pupils rather than through non-dilated pupils was tested. PATIENTS AND METHODS One eye each of 36 subjects (12 normal, 12 suspected glaucoma, and 12 glaucoma) was scanned using a single GDx unit with variable corneal compensator (GDx-VCC; Laser Diagnostic Technologies, Inc., Sa...