The present study evaluated the hemostatic efficacy and handling of gelatin-thrombin matrix hemostatic sealant during intracranial procedures. A retrospective analysis of 478 consecutive patients undergoing intracranial procedures identified seven patients with acute intense or persistent intraoperative bleeding which could not be arrested in time by standard hemostatic methods. The efficacy of...

AIM Adhesion after pelvic surgery causes infertility, ectopic pregnancy, and ileus or abdominal pain. The materials currently available for clinical use are insufficient. The purpose of this study was to develop an anti-adhesive material that overcomes the limitations of conventional anti-adhesive agents. METHODS The adhesion prevention effects of three methods - a two-layered sheet composed ...

Mesenchymal stem cell (MSC)-based therapies are emerging as promising approach to treat chronic wounds, although uncontrolled/sub-optimal delivery represents a major threat their wide-spread clinical adoption. Here we report comprehensive pre-clinical evaluation program on the mechanism of action, efficacy and safety an easy-to-use patch that concentrates MSC extracted from human fat (ASCs) in ...

One of the prawn rearing method had been using artificial feed of gelatin-acacia microcapsule. Characteristics of this microcapsule is very small and its size can be predicted and its density is as same as sea water.This study aimed to measure size distribution of fish oil droplet and the gelatin-acacia membrane was calculated in order to get the same density of sea water. Results of this study...

Experiments were carried out on a freshwater sponge (Ephydatia mulleri) in order to demonstrate the presence of fibronectin in Porifera. By using antibodies to highly purified human plasma fibronectin, the presence of a similar or identical protein could be demonstrated in the membranes of E. mulleri cells such as epithelial cells, fibroblast-like cells, and choanocytes. The reaction was specif...

Mutable collagenous tissues (MCTs) of echinoderms show reversible changes in tensile properties (mutability) that are initiated and modulated by the nervous system via the activities of cells known as juxtaligamental cells. The molecular mechanism underpinning this mechanical adaptability has still to be elucidated. Adaptable connective tissues are also present in mammals, most notably in the u...

Nanofiber Sponges In article number 2100918, Jinglei Wu, Xiumei Mo, and co-workers develop a novel conjugate electrospinning strategy to prepare 3D nanofiber sponge with low density, high surface area, compressibility. This method can be widely used in the preparation of various polymer sponges. The obtained gelatin holds great potential as an absorbable hemostatic agent for rapid hemostasis.

BACKGROUND AND PURPOSE Trisacryl gelatin microspheres are a new, commercially available nonabsorbable embolic agent. The purpose of this study was to evaluate their efficacy in the preoperative embolization of meningiomas as compared with polyvinyl alcohol (PVA) particles of various sizes. METHODS In 30 consecutive patients, trisacryl gelatin microspheres (150-300 microm) were used for the pr...

727 Abstract: The gelatin cap-sule shell may be soft or hard depending on their formulation. Capsules are intended to be swallowed whole by the patient. In instances where patients (especially children) are unable to swallow capsules, the contents of the capsule can be removed and added (e.g., sprinkled) on soft food immediately before ingestion. In the manufacture of pharmaceuticals, encapsula...

Objective; Tympanosclerosis is a common sequela of tympanoplasty operations causing hearing disability. It is associated with an increased production of free radicals (also known as reactive oxygen species) after trauma. Vitamin E is a scavenger of different free radicals by working as an antioxidant. The aim of the present study was to evaluate the effect of vitamin E-soaked absorbable gelatin...