نتایج جستجو برای: genetic predisposition to disease

تعداد نتایج: 11159105  

Journal: :British Medical Bulletin 2016

Journal: :British Journal of Cancer 1990

2017

The genetic component appears to be inherited in an autosomal dominant fashion. This means that each child has a 50% chance of inheriting. The genetic variant(s) can be inherited from either the father or the mother, and can be passed along to both sons and daughters. Current understanding of the pathogenesis of the syndrome suggests, that it is a complex multigenic disorder (a genetic problem ...

Journal: :American journal of epidemiology 2002
Wylie Burke David Atkins Marta Gwinn Alan Guttmacher James Haddow Joseph Lau Glenn Palomaki Nancy Press C Sue Richards Louise Wideroff Georgia L Wiesner

Growing knowledge about gene-disease associations will lead to new opportunities for genetic testing. Many experts predict that genetic testing will become increasingly important as a guide to prevention, clinical management, and drug treatment based on genetic susceptibilities. As part of a Human Genetic Epidemiology workshop convened by the Centers for Disease Control and Prevention, a group ...

Journal: :Clinical medicine 2005
Clare Turnbull Shirley Hodgson

Over recent decades a number of genes causing predisposition to cancer have been identified. Some of these cause rare autosomal dominant monogenic cancer predisposition syndromes. In the majority of families, the increased incidence of cancers is due to a multifactorial aetiology with a number of lower penetrance cancer predisposition genes interacting with environmental factors. Identification...

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